[HTML][HTML] Epidemiology of AKI: utilizing large databases to determine the burden of AKI

S Sawhney, SD Fraser - Advances in chronic kidney disease, 2017 - Elsevier
Large observational databases linking kidney function and other routine patient health data
are increasingly being used to study acute kidney injury (AKI). Routine health care data …

DEM simulation of continuous tablet coating: Effects of tablet shape and fill level on inter-tablet coating variability

…, G Toschkoff, S Radl, D Machold, SD Fraser… - Chemical engineering …, 2012 - Elsevier
Tablet coating is a common pharmaceutical technique of applying a thin polymer-based film
to a tablet or a granule containing active pharmaceutical ingredients (APIs). Inter- and intra-…

KDIGO-based acute kidney injury criteria operate differently in hospitals and the community—findings from a large population cohort

S Sawhney, N Fluck, SD Fraser, A Marks… - Nephrology Dialysis …, 2016 - academic.oup.com
Background Early recognition of acute kidney injury (AKI) is important. It frequently develops
first in the community. KDIGO-based AKI e-alert criteria may help clinicians recognize AKI in …

Continuous quantitative monitoring of powder mixing dynamics by near-infrared spectroscopy

…, G Hörl, C Voura, S Radl, N Urbanetz, SD Fraser… - Powder technology, 2011 - Elsevier
FT-NIR spectroscopy with a fiber optical reflection probe was applied as a process analytical
technology tool for the continuous quantitative in-line monitoring of pharmaceutical powder …

[HTML][HTML] Reduced expression of monocyte CD200R is associated with enhanced proinflammatory cytokine production in sarcoidosis

SD Fraser, LR Sadofsky, PM Kaye, SP Hart - Scientific reports, 2016 - nature.com
In sarcoidosis, the proinflammatory cytokines interferon gamma, tumour necrosis factor and
interleukin-6 are released by monocyte-derived macrophages and lymphocytes in the lungs …

[HTML][HTML] Aspirin to target arterial events in chronic kidney disease (ATTACK): study protocol for a multicentre, prospective, randomised, open-label, blinded endpoint …

…, P Stevens, MW Taal, D Stevenson, SD Fraser… - Trials, 2022 - Springer
Background Chronic kidney disease (CKD) is a very common long-term condition and powerful
risk factor for cardiovascular disease (CVD). Low-dose aspirin is of proven benefit in the …

Azithromycin for sarcoidosis cough: an open-label exploratory clinical trial

SD Fraser, S Thackray-Nocera, M Shepherd… - ERJ Open …, 2020 - Eur Respiratory Soc
Background Chronic cough is a distressing symptom for many people with pulmonary
sarcoidosis. Continuous treatment with a macrolide antibiotic may improve cough. We aimed to …

International comparison of trends in patients commencing renal replacement therapy by primary renal disease

…, M Pippias, M Ferrer‐Alamar, P Finne, SD Fraser… - …, 2019 - Wiley Online Library
Aim To examine international time trends in the incidence of renal replacement therapy (RRT)
for end‐stage renal disease (ESRD) by primary renal disease (PRD). Methods Renal …

[HTML][HTML] Characterisation of a new human alveolar macrophage-like cell line (Daisy)

…, YA Hayman, J Vance, JL Cervantes, SD Fraser… - Lung, 2019 - Springer
Purpose There is currently no true macrophage cell line and in vitro experiments requiring
these cells currently require mitogenic stimulation of a macrophage precursor cell line (THP-1…

Theory and applications of cooling systems in lunar surface exploration

SD Fraser - Moon: Prospective Energy and Material Resources, 2012 - Springer
Introduction The thermal energy balance of any space mission element, whether it is a
spacecraft, a permanent and crewed lunar base, or a space suit, is derived as a function of heat …