The elevated risk of Parkinson’s disease in patients with diabetes might be mitigated depending
on the type of drugs prescribed to treat diabetes. Population data for risk of Parkinson’s …

Background Recent in vitro and animal experiments suggest that peroxisome proliferation-activated
receptor gamma (PPARɣ) agonist medications, such as antidiabetic glitazone (GTZ) …

Background In vitro and animal studies have suggested that trazodone, a licensed antidepressant,
may protect against dementia. However, no studies have been conducted to assess …

Purpose There is widespread concern about increases in antibiotic use, but comparative data
from different European countries on rates of use are lacking. This study was designed to …

Background The WHO Comprehensive Mental Health Action Plan 2013–2030 encourages
routine collection and reporting of a set of essential mental health indicators, including the …

Background Previous studies have reported an extremely unbalanced global access to opioid
analgesics. We aimed to determine contemporary trends and patterns of opioid analgesic …

Background Herpes zoster is common and can have serious consequences. Additionally,
emerging data suggest an increased risk of acute cardiovascular events following herpes …

Importance The risk of birth and neurodevelopmental complications with prenatal exposure
to antipsychotics is unclear. Objective To evaluate the association between prenatal …

Background and aims Lipid-modifying agents (LMAs) are increasingly used to reduce lipid
levels and prevent cardiovascular events but the magnitude of their consumption in different …

Objective To measure the association between orlistat and acute liver injury. Design Self
controlled case series study. Setting Population based primary care setting, United Kingdom. …