[HTML][HTML] Prevalence and natural history of depression after stroke: a systematic review and meta-analysis of observational studies
Background Depression is the most frequent psychiatric condition after stroke and is
associated with negative health outcomes. We aim to undertake a systematic review and meta-…
associated with negative health outcomes. We aim to undertake a systematic review and meta-…
Effects of testosterone on muscle strength, physical function, body composition, and quality of life in intermediate-frail and frail elderly men: a randomized, double-blind …
…, MJ Connolly, MDL O'Connell… - The Journal of …, 2010 - academic.oup.com
Context: Physical frailty is associated with reduced muscle strength, impaired physical function,
and quality of life. Testosterone (T) increases muscle mass and strength in hypogonadal …
and quality of life. Testosterone (T) increases muscle mass and strength in hypogonadal …
Diabetes as an independent risk factor for stroke recurrence in ischemic stroke patients: an updated meta-analysis
L Zhang, X Li, CDA Wolfe, MDL O'Connell… - Neuroepidemiology, 2021 - karger.com
Introduction: Stroke and its recurrence and diabetes will increase in incidence as the
population ages globally. This study explores the relationship between diabetes and stroke …
population ages globally. This study explores the relationship between diabetes and stroke …
[HTML][HTML] Androgen effects on skeletal muscle: implications for the development and management of frailty
MDL O'Connell, FCW Wu - Asian journal of andrology, 2014 - journals.lww.com
Androgens have potent anabolic effects on skeletal muscle and decline with age in parallel
to losses in muscle mass and strength. This loss of muscle mass and function, known as …
to losses in muscle mass and strength. This loss of muscle mass and function, known as …
Age-related normative changes in phasic orthostatic blood pressure in a large population study: findings from The Irish Longitudinal Study on Ageing (TILDA)
C Finucane, MDL O'Connell, CW Fan, GM Savva… - Circulation, 2014 - Am Heart Assoc
Background— In this report, we provide the first normative reference data and prevalence
estimates of impaired orthostatic blood pressure (BP) stabilization, initial orthostatic …
estimates of impaired orthostatic blood pressure (BP) stabilization, initial orthostatic …
The ability of three different models of frailty to predict all-cause mortality: results from the European Male Aging Study (EMAS)
…, N Pendleton, JD Finn, A Tajar, MDL O'Connell… - Archives of gerontology …, 2013 - Elsevier
Few studies have directly compared the ability of the most commonly used models of frailty
to predict mortality among community-dwelling individuals. Here, we used a frailty index (FI), …
to predict mortality among community-dwelling individuals. Here, we used a frailty index (FI), …
Impaired orthostatic blood pressure recovery is associated with unexplained and injurious falls
C Finucane, MDL O'Connell… - Journal of the …, 2017 - Wiley Online Library
Objectives Cardiovascular disorders are recognized as important modifiable risk factors for
falls. However, the association between falls and orthostatic hypotension ( OH ) remains …
falls. However, the association between falls and orthostatic hypotension ( OH ) remains …
The association of frailty with serum 25-hydroxyvitamin D and parathyroid hormone levels in older European men
Background: the link between the vitamin D endocrine axis and frailty remains undefined,
with few studies examining the joint effect of vitamin D and parathyroid hormone (PTH) levels. …
with few studies examining the joint effect of vitamin D and parathyroid hormone (PTH) levels. …
[HTML][HTML] The relationship between increased body mass index and frailty on falls in community dwelling older adults
KJ Sheehan, MDL O'Connell, C Cunningham… - BMC geriatrics, 2013 - Springer
Background The global population is becoming older and more overweight. The inter-relationship
between frailty and falls is often seen in the older adult and is associated with poor …
between frailty and falls is often seen in the older adult and is associated with poor …
Do the effects of testosterone on muscle strength, physical function, body composition, and quality of life persist six months after treatment in intermediate-frail and frail …
MDL O'Connell, SA Roberts… - The Journal of …, 2011 - academic.oup.com
Context: Short-term testosterone (T) treatment in frail elderly men improves muscle mass and
strength. It is unclear whether these effects can be maintained post treatment. Objective: To …
strength. It is unclear whether these effects can be maintained post treatment. Objective: To …