Should chloroquine and hydroxychloroquine be used to treat COVID-19? A rapid review

K Gbinigie, K Frie - BJGP open, 2020 - bjgpopen.org
Background On the 11 March 2020, the World Health Organization (WHO) declared that
COVID-19 was a pandemic. To date, there are no medical treatments for COVID-19 with proven …

Should azithromycin be used to treat COVID-19? A rapid review

K Gbinigie, K Frie - BJGP open, 2020 - bjgpopen.org
Background There are no established effective treatments for COVID-19. While novel drugs
are being developed, azithromycin has been identified as a candidate treatment in the …

Lopinavir/ritonavir: A rapid review of effectiveness in COVID-19

J Dorward, K Gbinigie - 2020 - covid19-evidence.paho.org
There are currently no pharmacological treatments for COVID-19. Due to the urgent need for
effective treatments, there has been increased interest in re-purposing currently available …

PRINCIPLE trial demonstrates scope for in-pandemic improvement in primary care antibiotic stewardship: a retrospective sentinel network cohort study

…, J Sherlock, M Tripathy, O van Hecke, K Gbinigie… - BJGP open, 2021 - bjgpopen.org
Background The Platform Randomised trial of INterventions against COVID-19 In older
peoPLE (PRINCIPLE) has provided in-pandemic evidence that azithromycin and doxycycline …

[PDF][PDF] Chloroquine and hydroxychloroquine: current evidence for their effectiveness in treating COVID-19

K Frie, K Gbinigie - Centre Evid Based Med, 2020 - affinityhealth.co.za
BACKGROUND Chloroquine (CQ) was first used as prophylaxis and treatment for malaria.
Hydroxychloroquine (HCQ) is a more soluble and less toxic metabolite of chloroquine, which …

[PDF][PDF] BJGP Open

…, J Sherlock, M Tripathy, O van Hecke, K Gbinigie… - 2021 - bjgpopen.org
Background: The Platform Randomised trial of INterventions against COVID-19 In older
peoPLE (PRINCIPLE) has provided in-pandemic evidence that azithromycin and doxycycline …

[HTML][HTML] Centre for Evidence Based Medicine

J Dorward, K Gbinigie - 2020 - cebm.net
… Jienchi Dorward and Kome Gbinigie … Jienchi Dorward* and Kome Gbinigie* are both
General Practitioners and doctoral researchers based at the Nuffield Department of Primary …

[HTML][HTML] The Centre for Evidence-Based Medicine

K Frie, K Gbinigie - cebm.net
… Kerstin Frie and Kome Gbinigie … Correspondence to oghenekome.gbinigie@phc.ox.ac.uk …
Kome Gbinigie* is a General Practitioner and doctoral researcher based at the Nuffield …

[HTML][HTML] Randomized controlled trial of molnupiravir SARS-CoV-2 viral and antibody response in at-risk adult outpatients

…, A Shields, AG Richter, J Dorward, O Gbinigie… - Nature …, 2024 - nature.com
Viral clearance, antibody response and the mutagenic effect of molnupiravir has not been
elucidated in at-risk populations. Non-hospitalised participants within 5 days of SARS-CoV-2 …

[CITATION][C] What is the evidence for using macrolide antibiotics to treat COVID-19

K Gbinigie, K Frie - The Centre for Evidence-Based Medicine, 2020