Background Parkinson's disease has an insidious onset and is diagnosed when typical motor
features occur. Several motor and non-motor features can occur before diagnosis, early in …

Background two popular operational definitions of frailty, the frailty phenotype and Frailty
index (FI), are based on different theories. Although FI was shown to be superior in predicting …

Objective To systematically review the research conducted on prevalence of frailty and
prefrailty among community-dwelling older adults in low-income and middle-income countries (…

Objectives To describe the incidence of recorded mental illness and challenging behaviour
in people with intellectual disability in UK primary care and to explore the prescription of …

BackgroundBipolar disorder and schizophrenia are associated with increased mortality relative
to the general population. There is an international emphasis on decreasing this excess …

Background With growing numbers of older people worldwide, improving and maintaining
quality of life during the extended years of life are a major focus for healthcare providers and …

Japan's population is aging more rapidly than that of any other country. Frailty has recently
been recognized as an important priority. Understanding the basic epidemiology of frailty in …

RESEARCH Page 1 RESEARCH Survival of people with clinical diagnosis of dementia in
primary care: cohort study Greta Rait, senior clinical scientist,1 Kate Walters, senior lecturer in …

Frailty is a well-established risk factor for adverse health outcomes. However, comparatively
little is known about the dynamic nature of frailty and the extent to which it can improve. The …

Objective To perform a systematic search of the literature for currently available evidence on
frailty as a predictor of dementia and to conduct a meta-analysis to synthesize the pooled …