[HTML][HTML] Causes and consequences of HPV integration in head and neck squamous cell carcinomas: state of the art

H Balaji, I Demers, N Wuerdemann, J Schrijnder… - Cancers, 2021 - mdpi.com
Simple Summary In human papillomavirus (HPV) associated head and neck squamous cell
carcinomas (HNSCC) s, the HPV genome is commonly found integrated in the human …

Evaluation of the sensitivity of metabolic profiling by rapid evaporative ionization mass spectrometry: toward more radical oral cavity cancer resections

PM Vaysse, I Demers, MFCM van den Hout… - Analytical …, 2022 - ACS Publications
Radical resection for patients with oral cavity cancer remains challenging. Rapid evaporative
ionization mass spectrometry (REIMS) of electrosurgical vapors has been reported for real-…

[HTML][HTML] Ex vivo culture models to indicate therapy response in head and neck squamous cell carcinoma

I Demers, J Donkers, B Kremer, EJ Speel - Cells, 2020 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is characterized by a poor 5 year
survival and varying response rates to both standard-of-care and new treatments. Despite …

[HTML][HTML] Predicting HPV association using deep learning and regular H&E stains allows granular stratification of oropharyngeal cancer patients

S Klein, N Wuerdemann, I Demers, C Kopp… - npj Digital …, 2023 - nature.com
Human Papilloma Virus (HPV)-associated oropharyngeal squamous cell cancer (OPSCC)
represents an OPSCC subgroup with an overall good prognosis with a rising incidence in …

Public awareness of the association between human papillomavirus and oropharyngeal cancer

F Verhees, I Demers, LJ Schouten… - European Journal of …, 2021 - academic.oup.com
Background Early diagnosis of human papillomavirus (HPV) associated oropharyngeal
cancer (OPC) is associated with improved survival. To achieve early diagnosis, it might be …

Switches of SOX17 and SOX2 expression in the development of squamous metaplasia and squamous intraepithelial lesions of the uterine cervix

…, KAD Wouters, H Stoop, I Demers… - Cancer …, 2020 - Wiley Online Library
Aims The dynamics and topographical distribution of SOX17 and SOX2 expression was
studied in the transformation zone (TZ) of the uterine cervix. This TZ is a dynamic area where …

[HTML][HTML] The antiviral agent cidofovir induces DNA damage and mitotic catastrophe in HPV-positive and-negative head and neck squamous cell carcinomas in vitro

F Verhees, D Legemaate, I Demers, R Jacobs… - Cancers, 2019 - mdpi.com
Cidofovir (CDV) is an antiviral agent with antiproliferative properties. The aim of our study was
to investigate the efficacy of CDV in HPV-positive and -negative head and neck squamous …

[HTML][HTML] GABARAPL1 is essential in extracellular vesicle cargo loading and metastasis development

JEJ Beaumont, J Ju, LMO Barbeau, I Demers… - Radiotherapy and …, 2024 - Elsevier
Background and purpose Hypoxia is a common feature of tumours, associated with poor
prognosis due to increased resistance to radio- and chemotherapy and enhanced metastasis …

Awareness of HPV-associated oropharyngeal cancers among GPs in The Netherlands: a cross-sectional study

I Demers, F Verhees, LJ Schouten, JWM Muris… - BJGP open, 2022 - bjgpopen.org
Background The incidence of human papillomavirus (HPV)-associated oropharyngeal cancer
(OPC) is increasing in high income countries. HPV-associated OPC generally presents as …

[PDF][PDF] Public awareness of the association between human papillomavirus and oropharyngeal cancer in the Netherlands

F Verhees, I Demers, LJ Schouten… - … to decrease the …, 2024 - cris.maastrichtuniversity.nl
Background Early diagnosis of human papillomavirus (HPV) associated oropharyngeal
cancer (OPC) is associated with improved survival. To achieve early diagnosis, it might be …