User profiles for Henkjan Verkade
 | Henkjan VerkadeProfessor of Pediatrics, University of Groningen, University Medical Center Groningen, The … Verified email at umcg.nl Cited by 13692 |
The EASL–Lancet Liver Commission: protecting the next generation of Europeans against liver disease complications and premature mortality
…, A Lerouge, M Devaux, N Scott, M Hellard, HJ Verkade… - The Lancet, 2022 - thelancet.com
Liver diseases have become a major health threat across Europe, and the face of European
hepatology is changing due to the cure of viral hepatitis C and the control of chronic viral …
hepatology is changing due to the cure of viral hepatitis C and the control of chronic viral …
[HTML][HTML] Stimulation of lipogenesis by pharmacological activation of the liver X receptor leads to production of large, triglyceride-rich very low density lipoprotein …
The oxysterol-activated liver X receptor (LXR) provides a link between sterol and fatty acid
metabolism; activation of LXR induces transcription of lipogenic genes. This study shows that …
metabolism; activation of LXR induces transcription of lipogenic genes. This study shows that …
Abnormal liver function tests in patients with COVID‐19: relevance and potential pathogenesis
…, R Fiorotto, JW Jonker, M Strazzabosco, HJ Verkade… - Hepatology, 2020 - journals.lww.com
Lipopolysaccharide Reverses Hepatic Stellate Cell Activation... : Hepatology Lipopolysaccharide
Reverses Hepatic Stellate Cell Activation Through Modulation of cMyb, Small Mothers Against …
Reverses Hepatic Stellate Cell Activation Through Modulation of cMyb, Small Mothers Against …
Severe bile salt export pump deficiency: 82 different ABCB11 mutations in 109 families
…, F Özçay, HF Al–Hussaini, AF Bassas, HJ Verkade… - Gastroenterology, 2008 - Elsevier
Background & Aims: Patients with severe bile salt export pump (BSEP) deficiency present as
infants with progressive cholestatic liver disease. We characterized mutations of ABCB11 (…
infants with progressive cholestatic liver disease. We characterized mutations of ABCB11 (…
Diagnosis and management of pediatric autoimmune liver disease: ESPGHAN hepatology committee position statement
…, G Indolfi, J Jahnel, F Smets, HJ Verkade… - Journal of pediatric …, 2018 - journals.lww.com
Paediatric autoimmune liver disease is characterized by inflammatory liver histology, circulating
autoantibodies, and increased levels of IgG, in the absence of a known etiology. Three …
autoantibodies, and increased levels of IgG, in the absence of a known etiology. Three …
Wilson's disease in children: a position paper by the Hepatology Committee of the European Society for Paediatric Gastroenterology, Hepatology and Nutrition
Background: Clinical presentations of Wilson's disease (WD) in childhood ranges from
asymptomatic liver disease to cirrhosis or acute liver failure, whereas neurological and psychiatric …
asymptomatic liver disease to cirrhosis or acute liver failure, whereas neurological and psychiatric …
Regulation of cholesterol homeostasis
MYM van der Wulp, HJ Verkade, AK Groen - Molecular and cellular …, 2013 - Elsevier
Hypercholesterolemia is an important risk factor for cardiovascular disease. It is caused by a
disturbed balance between cholesterol secretion into the blood versus uptake. The …
disturbed balance between cholesterol secretion into the blood versus uptake. The …
[HTML][HTML] Odevixibat treatment in progressive familial intrahepatic cholestasis: a randomised, placebo-controlled, phase 3 trial
…, N Soufi, E Sturm, ME Tessier, HJ Verkade… - The Lancet …, 2022 - thelancet.com
Background Progressive familial intrahepatic cholestasis (PFIC) is a group of inherited paediatric
liver diseases resulting from mutations in genes that impact bile secretion. We aimed to …
liver diseases resulting from mutations in genes that impact bile secretion. We aimed to …
Differential effects of eicosapentaenoic acid on glycerolipid and apolipoprotein B metabolism in primary human hepatocytes compared to HepG2 cells and primary rat …
Y Lin, MJ Smit, R Havinga, HJ Verkade, RJ Vonk… - … et Biophysica Acta (BBA …, 1995 - Elsevier
We compared the effects of eicosapentaenoic acid (EPA) and oleic acid (OA) on glycerolipid
and apolipoprotein B (apoB) metabolism in primary human hepatocytes, HepG2 cells and …
and apolipoprotein B (apoB) metabolism in primary human hepatocytes, HepG2 cells and …
[PDF][PDF] Graft fibrosis after pediatric liver transplantation: ten years of follow‐up
R Scheenstra, PMGJ Peeters, HJ Verkade… - …, 2009 - Wiley Online Library
Previously we reported the presence of portal fibrosis in 31% (n = 84) of the grafts in protocol
biopsies 1 year after pediatric liver transplantation (LTx). To assess the natural history of …
biopsies 1 year after pediatric liver transplantation (LTx). To assess the natural history of …