Development and validation of a staging system for HPV-related oropharyngeal cancer by the International Collaboration on Oropharyngeal cancer Network for …
…, AB Gothelf, F Hoebers, B Kremer, EJ Speel… - The Lancet …, 2016 - thelancet.com
Background Human papillomavirus-related (HPV+) oropharyngeal cancer is a rapidly emerging
disease with generally good prognosis. Many prognostic algorithms for oropharyngeal …
disease with generally good prognosis. Many prognostic algorithms for oropharyngeal …
Loss of DAXX and ATRX are associated with chromosome instability and reduced survival of patients with pancreatic neuroendocrine tumors
…, T Rudolph, V Banz, F Hunger, S Pasquinelli, EJ Speel… - Gastroenterology, 2014 - Elsevier
Background & Aims Sporadic pancreatic neuroendocrine tumors (pNETs) are rare and
genetically heterogeneous. Chromosome instability (CIN) has been detected in pNETs from …
genetically heterogeneous. Chromosome instability (CIN) has been detected in pNETs from …
Early B-cell differentiation in Merkel cell carcinomas: clues to cellular ancestry
…, D Rennspiess, V Winnepenninckx, EJ Speel… - Cancer research, 2013 - AACR
Merkel cell carcinoma (MCC) is a highly malignant neuroendocrine nonmelanoma skin cancer,
which is associated with the Merkel cell polyoma virus (MCPyV). Recently, expression of …
which is associated with the Merkel cell polyoma virus (MCPyV). Recently, expression of …
Comparison of three PD-L1 immunohistochemical assays in head and neck squamous cell carcinoma (HNSCC)
EJ de Ruiter, FJ Mulder, BM Koomen, EJ Speel… - Modern …, 2021 - nature.com
Expression of programmed cell death-ligand 1 (PD-L1) is being used as predictive
biomarker for immunotherapy in head and neck squamous cell carcinoma (HNSCC). Several …
biomarker for immunotherapy in head and neck squamous cell carcinoma (HNSCC). Several …
[HTML][HTML] Ex vivo culture models to indicate therapy response in head and neck squamous cell carcinoma
I Demers, J Donkers, B Kremer, EJ Speel - Cells, 2020 - mdpi.com
Head and neck squamous cell carcinoma (HNSCC) is characterized by a poor 5 year
survival and varying response rates to both standard-of-care and new treatments. Despite …
survival and varying response rates to both standard-of-care and new treatments. Despite …
Radiosensitivity and effect of hypoxia in HPV positive head and neck cancer cells
BS Sørensen, M Busk, N Olthof, EJ Speel… - Radiotherapy and …, 2013 - Elsevier
Background and purpose HPV associated Head and Neck Squamous Cell Carcinoma (HNSCC)
represents a distinct subgroup of HNSCC characterized by a favorable prognosis and a …
represents a distinct subgroup of HNSCC characterized by a favorable prognosis and a …
[HTML][HTML] Orthopedia homeobox (OTP) in pulmonary neuroendocrine tumors: the diagnostic value and possible molecular interactions
L Moonen, J Derks, AM Dingemans, EJ Speel - Cancers, 2019 - mdpi.com
Generally, patients with stage I-IIIa (TNM) pulmonary carcinoid disease have a favourable
prognosis after curative resection. Yet, distant recurrence of disease after curative surgery …
prognosis after curative resection. Yet, distant recurrence of disease after curative surgery …
[HTML][HTML] Externally validated HPV-based prognostic nomogram for oropharyngeal carcinoma patients yields more accurate predictions than TNM staging
…, RH Brakenhoff, RC Leemans, EJ Speel… - Radiotherapy and …, 2014 - Elsevier
Purpose Due to the established role of the human papillomavirus (HPV), the optimal treatment
for oropharyngeal carcinoma is currently under debate. We evaluated the most important …
for oropharyngeal carcinoma is currently under debate. We evaluated the most important …
[HTML][HTML] Evaluation of NGS and RT-PCR methods for ALK rearrangement in European NSCLC patients: results from the European Thoracic Oncology Platform …
…, P Smyth, A Soltermann, L Bubendorf, EJ Speel… - Journal of Thoracic …, 2018 - Elsevier
Introduction The reported prevalence of ALK receptor tyrosine kinase gene (ALK)
rearrangement in NSCLC ranges from 2% to 7%. The primary standard diagnostic method is …
rearrangement in NSCLC ranges from 2% to 7%. The primary standard diagnostic method is …
[PDF][PDF] Validation of a gene expression signature for assessment of lymph node metastasis in oral squamous cell carcinoma
…, FK Leusink, P Roepman, RJB De Jong, EJ Speel… - J Clin Oncol, 2012 - academia.edu
Purpose Current assessment of lymph node metastasis in patients with head and neck
squamous cell carcinoma is not accurate enough to prevent overtreatment. The aim of this study …
squamous cell carcinoma is not accurate enough to prevent overtreatment. The aim of this study …