Background The comparative effectiveness of treatments for prostate cancer that is detected
by prostate-specific antigen (PSA) testing remains uncertain. Methods We compared active …

Objective To systematically review the literature and, where appropriate, meta-analyse
studies investigating subsequent antibiotic resistance in individuals prescribed antibiotics in …

Background Between 1999 and 2009 in the United Kingdom, 82,429 men between 50 and
69 years of age received a prostate-specific antigen (PSA) test. Localized prostate cancer …

Background Robust data on patient-reported outcome measures comparing treatments for
clinically localized prostate cancer are lacking. We investigated the effects of active monitoring…

Micronucleus assays with fish have been shown to be useful in vivo techniques for genotoxicity
testing, and show potential for in situ monitoring of water quality. In this paper, we review …

To investigate the occurrence of antimicrobials in the final effluents from wastewater
treatment plants (WWTPs) in Canada, analytical methods were developed or modified from …

Prescription and nonprescription drugs have been detected in rivers and streams in Europe
and the United States. Sewage treatment plants (STPs) are an important source of these …

Gonadal intersex and high prevalences of the female phenotype have been observed in fish
populations in urbanized areas. Environmental estrogens discharged in sewage treatment …

Samples of influent (untreated) and effluent (treated) from 18 sewage treatment plants (STPs)
in 14 municipalities in Canada were analyzed for residues of selected prescription and …

The risks associated with exposure to engineered nanomaterials (ENM) will be determined
in part by the processes that control their environmental fate and transformation. These …