Older people are disproportionately affected by the COVID-19 pandemic, which has had a
profound impact on research as well as clinical service delivery. This commentary identifies …

Stem cells are types of cells that have unique ability to self-renew and to differentiate into
more than one cell lineage. They are considered building blocks of tissues and organs. Over …

Background: The long-term treatment of Parkinson disease (PD) may be complicated by the
development of levodopa-induced dyskinesia. Clinical and animal model data support the …

Many now believe the holy grail for the next stage of therapeutic advance surrounds the
development of disease-modifying approaches aimed at intercepting the year-on-year …

… Parkinson's disease - Carroll - 2012 - Neuropathology and Applied Neurobiology - Wiley
Online Library … Dr Carroll was an MRC post-doctoral fellow at the time of undertaking this work. …

In this study, we quantify the severity of drug-induced dyskinesias in the arms of Parkinson's
disease (PD) patients using digitised spiral-drawing tasks. Two spiral drawings, namely a …

Introduction Parkinson’s disease (PD) is a common neurodegenerative disorder with substantial
morbidity. No disease-modifying treatments currently exist. The glucagon like peptide-1 …

Iron misregulation promotes oxidative stress and abnormally high iron levels have been
found in the spinal cords of patients with ALS. The authors investigated whether HFE gene …

Introduction There is an ongoing digital revolution in the field of Parkinson's disease (PD)
for the objective measurement of motor aspects, to be used in clinical trials and possibly …

Objective To provide guidance to researchers, funders, regulators and study delivery teams
to ensure that research on COVID-19 is inclusive, particularly of groups disproportionately …