Aims An invasive approach is superior to medical management for the treatment of patients
with acute coronary syndromes without ST-segment elevation (NSTE-ACS), but the optimal …

Background A routine invasive strategy is recommended for patients with non-ST-elevation
acute coronary syndromes (NSTE-ACS). However, optimal timing of invasive strategy is less …

Background New-generation drug-eluting stents (DES) have mostly been investigated in
head-to-head non-inferiority trials against early-generation DES and have typically shown …

Background—The primary objective of reperfusion therapies for acute myocardial infarction
is not only restoration of blood flow in the epicardial coronary artery but also complete and …

Background As compared with thrombolytic therapy, primary coronary angioplasty results in
a higher rate of patency of the infarct-related coronary artery, lower rates of stroke and …

… Arnaud van't Hof coordinated this project and collated, checked, and analysed the data
specific to this part of the Zwolle Myocardial Infarction Study. Aylee Liem assisted in data …

Background The most effective magnitude and timing of antiplatelet therapy is important in
patients with acute ST-elevation myocardial infarction (STEMI). We investigated whether the …

Objectives : The aim of the study was to evaluate the relationship between symptom-onset-to-balloon
time and one-year mortality in patients with ST-segment elevation myocardial …

Background It is unknown whether patients undergoing primary percutaneous coronary
intervention (PCI) benefit from genotype-guided selection of oral P2Y 12 inhibitors. Methods We …

Background— Angiographic successful reperfusion in acute myocardial infarction has been
defined as TIMI 3 flow. However, TIMI 3 flow does not always result in effective myocardial …