Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci
…, X Ke, AT Lee, X Liu, P Martin, AW Morgan… - Nature …, 2010 - nature.com
To identify new genetic risk factors for rheumatoid arthritis, we conducted a genome-wide
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …
association study meta-analysis of 5,539 autoantibody-positive individuals with rheumatoid …
Interaction between ERAP1 and HLA-B27 in ankylosing spondylitis implicates peptide handling in the mechanism for HLA-B27 in disease susceptibility
…, A Morgan… - Nature …, 2011 - nature.com
Ankylosing spondylitis is a common form of inflammatory arthritis predominantly affecting
the spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent. …
the spine and pelvis that occurs in approximately 5 out of 1,000 adults of European descent. …
2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for granulomatosis with polyangiitis
…, J Mclaren, M Morgan, A Morgan… - Arthritis & …, 2022 - Wiley Online Library
Objective To develop and validate revised classification criteria for granulomatosis with
polyangiitis (GPA). Methods Patients with vasculitis or comparator diseases were recruited into …
polyangiitis (GPA). Methods Patients with vasculitis or comparator diseases were recruited into …
2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for eosinophilic granulomatosis with polyangiitis
…, J Mclaren, M Morgan, A Morgan… - Arthritis & …, 2022 - Wiley Online Library
Objective To develop and validate revised classification criteria for eosinophilic granulomatosis
with polyangiitis (EGPA). Methods Patients with vasculitis or comparator diseases were …
with polyangiitis (EGPA). Methods Patients with vasculitis or comparator diseases were …
2022 American College of Rheumatology/European Alliance of Associations for Rheumatology classification criteria for microscopic polyangiitis
…, J Mclaren, M Morgan, A Morgan… - Arthritis & …, 2022 - Wiley Online Library
Objective To develop and validate classification criteria for microscopic polyangiitis (MPA).
Methods Patients with vasculitis or comparator diseases were recruited into an international …
Methods Patients with vasculitis or comparator diseases were recruited into an international …
An ultraviolet-radiation-independent pathway to melanoma carcinogenesis in the red hair/fair skin background
People with pale skin, red hair, freckles and an inability to tan—the ‘red hair/fair skin’
phenotype—are at highest risk of developing melanoma, compared to all other pigmentation types …
phenotype—are at highest risk of developing melanoma, compared to all other pigmentation types …
Genetic variants at CD28, PRDM1 and CD2/CD58 are associated with rheumatoid arthritis risk
To discover new rheumatoid arthritis (RA) risk loci, we systematically examined 370 SNPs
from 179 independent loci with P < 0.001 in a published meta-analysis of RA genome-wide …
from 179 independent loci with P < 0.001 in a published meta-analysis of RA genome-wide …
The requirement for DNAM-1, NKG2D, and NKp46 in the natural killer cell-mediated killing of myeloma cells
…, TD Holmes, D McGonagle, SL Mackie, AW Morgan… - Cancer research, 2007 - AACR
Recent evidence suggests a role for natural killer (NK) cells in the control of multiple myeloma.
We show that expression of the NK cell receptor DNAM-1 (CD226) is reduced on CD56 …
We show that expression of the NK cell receptor DNAM-1 (CD226) is reduced on CD56 …
2022 American College of Rheumatology/EULAR classification criteria for Takayasu arteritis
…, J Mclaren, M Morgan, A Morgan… - Arthritis & …, 2022 - Wiley Online Library
Objective To develop and validate new classification criteria for Takayasu arteritis (TAK).
Methods Patients with vasculitis or comparator diseases were recruited into an international …
Methods Patients with vasculitis or comparator diseases were recruited into an international …
Rheumatoid arthritis association at 6q23
The Wellcome Trust Case Control Consortium (WTCCC) identified nine single SNPs
putatively associated with rheumatoid arthritis at P = 1 × 10 −5 − 5 × 10 −7 in a genome-wide …
putatively associated with rheumatoid arthritis at P = 1 × 10 −5 − 5 × 10 −7 in a genome-wide …