Atrial fibrillation in 2011: Stroke prevention in AF

Nat Rev Cardiol. 2011 Dec 20;9(2):71-3. doi: 10.1038/nrcardio.2011.203.

Abstract

In 2011, key trials with oral factor Xa inhibitors in patients with atrial fibrillation highlighted promising data on these novel anticoagulants. Patients with ≥ 1 stroke risk factors can be considered for oral anticoagulation. These novel, fixed-dose drugs are given without monitoring, so clinicians must learn to balance stroke and bleeding risks.

Publication types

  • Review

MeSH terms

  • Administration, Oral
  • Anticoagulants / administration & dosage
  • Anticoagulants / therapeutic use*
  • Atrial Fibrillation* / complications
  • Atrial Fibrillation* / drug therapy
  • Atrial Fibrillation* / physiopathology
  • Dose-Response Relationship, Drug
  • Factor Xa Inhibitors
  • Global Health
  • Humans
  • Incidence
  • Retrospective Studies
  • Risk Factors
  • Stroke* / epidemiology
  • Stroke* / etiology
  • Stroke* / prevention & control

Substances

  • Anticoagulants
  • Factor Xa Inhibitors