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Patient experiences with the performance of tablet score lines needed for dosing

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Abstract

Objective: The aim of this study was to measure the experience of patients with score line tablets where breaking was necessary for dosing. Method: In three community pharmacies in the Netherlands, patients were asked about their experiences with the functioning of the score line. The survey was restricted to scored tablets that had to be broken to obtain the prescribed dose. It was also asked what actions were taken by the patient when breaking problems were encountered.Results: Of all the score line prescriptions included in the study, 36% received a negative evaluation by the patient. The main negative experiences were related to loss of mass after breaking the tablets and difficulty in breaking, reported in 32% and 15%, respectively, of the prescriptions included in the study. In only 28% of the negative experiences had this been reported back to the pharmacy.Conclusion: Many patients experience an unsatisfactory performance of tablets with score lines. Improvement will need a combination of technically better score lines and the alertness of the dispensing pharmacy for breaking problems.

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References

  1. Anonymous. European Pharmacopoeia. 4. Strasbourg: European Directorate for the Quality of Medicines within the Council of Europe, 2002.

  2. Van Santen E, Barends DM, Frijlink HW. Breaking of scored tablets: a review. Eur J Pharm and Biopharm. 2002; 53: 139–45.

    Google Scholar 

  3. Overgaard ABA, Højsted J, Hansen R, Møller-Sonnergaard, Christrup LL. Patient's evaluation of shape, size and colour of solid dosage forms. Pharm World Sci 2001; 23: 185–8.

    Google Scholar 

  4. Anonymous. Farmacie in cijfers: vrouwen slikken meer. [Pharmacy in figures: women swallow more.] Pharm Weekbl 2001; 136: 779.

  5. Anonymous. College keurt breukgleuven af. [Board disapproves of score lines.] Pharm Weekbl 2000; 135(49):1816.

  6. McDevitt JT, Gurst AH, Chen Y. Accuracy of tablet splitting. Pharmacotherapy 1998; 18: 193–7.

    Google Scholar 

  7. Duman E, Yuksel N, Olin B, Sakr A. Effect of scoring design on the uniformity of extended release matrix tablet halves. Pharm Ind 2000; 62: 547–50.

    Google Scholar 

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Authors and Affiliations

  1. National Institute of Public Health and the Environment, Antonie van Leeuwenhoeklaan 9, P.O. Box 1, 3720 BA, Bilthoven, The Netherlands E‐mail

    N. Rodenhuis & D.M. Barends

  2. Wetenschappelijk Instituut Nederlandse Apothekers (WINAp), Alexanderstraat 11, P.O. Box 30460, 2500 GL, The Hague

    P.A.G.M. de Smet

  3. Academisch Ziekenhuis Nijmegen, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands

    P.A.G.M. de Smet

Authors
  1. N. Rodenhuis
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  2. D.M. Barends
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  3. P.A.G.M. de Smet
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Rodenhuis, N., Barends, D. & de Smet, P. Patient experiences with the performance of tablet score lines needed for dosing. Pharm World Sci 25, 173–176 (2003). https://doi.org/10.1023/A:1024852529628

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  • DOI: https://doi.org/10.1023/A:1024852529628

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