Elsevier

Manual Therapy

Volume 15, Issue 4, August 2010, Pages 334-354
Manual Therapy

Systematic review
Manual therapy and exercise for neck pain: A systematic review

https://doi.org/10.1016/j.math.2010.02.007Get rights and content

Abstract

Manual therapy is often used with exercise to treat neck pain. This cervical overview group systematic review update assesses if manual therapy, including manipulation or mobilisation, combined with exercise improves pain, function/disability, quality of life, global perceived effect, and patient satisfaction for adults with neck pain with or without cervicogenic headache or radiculopathy. Computerized searches were performed to July 2009. Two or more authors independently selected studies, abstracted data, and assessed methodological quality. Pooled relative risk (pRR) and standardized mean differences (pSMD) were calculated. Of 17 randomized controlled trials included, 29% had a low risk of bias. Low quality evidence suggests clinically important long-term improvements in pain (pSMD-0.87(95% CI:−1.69,−0.06)), function/disability, and global perceived effect when manual therapy and exercise are compared to no treatment. High quality evidence suggests greater short-term pain relief [pSMD-0.50(95% CI:−0.76,−0.24)] than exercise alone, but no long-term differences across multiple outcomes for (sub)acute/chronic neck pain with or without cervicogenic headache. Moderate quality evidence supports this treatment combination for pain reduction and improved quality of life over manual therapy alone for chronic neck pain; and suggests greater short-term pain reduction when compared to traditional care for acute whiplash. Evidence regarding radiculopathy was sparse. Specific research recommendations are made.

Section snippets

Background

Neck pain is a frequent impairment associated with disability and substantive health care costs (Côté et al., 1998; Linton et al., 1998; Borghouts et al., 1999; Hogg-Johnson et al., 2008). Manipulation, mobilisation, or exercise applied as single-modal treatment approaches for neck pain have gained some support in Cochrane reviews (Gross et al., 2010 found earlier in this issue of Manual Therapy; Kay et al., 2009). Many practitioners believe that solo-care approaches do not accurately represent

Objectives

Our systematic review update assesses the effectiveness of manual therapy and exercise for neck pain with or without radicular symptoms or cervicogenic headache on pain, function/disability, quality of life, global perceived effect, and patient satisfaction.

Study selection

Abbreviated inclusion criteria follow; see Gross et al., 2010 earlier in this issue for detailed definitions.

Description of studies

We selected 17 trials representing 31 publications from 1820 citation postings (See Fig. 1):

  • 17 studied neck pain: acute (Mealy et al., 1986, McKinney et al., 1989, Giebel et al., 1997, Bonk et al., 2000); subacute (Karlberg et al., 1996); chronic (Brodin, 1985, Vasseljen et al., 1995, Skargren and Oberg, 1998, Bronfort et al., 2001, Persson and Lilja, 2001, Allison et al., 2002, Jull et al., 2002, Ylinen et al., 2003, Palmgren et al., 2006, Walker et al., 2008); and mixed duration (Provinciali

Discussion

In our previous systematic review:

  • up to 1996 (Gross et al., 1996): results remained inconclusive for mobilisation or manipulation as a single intervention and suggested support for combined mobilisation, manipulation and exercise for short-term pain reduction.

  • up to 2003 (Gross et al., 2003): results showed no evidence in support of manipulation or mobilisation alone but showed further support to the use of combined mobilisation, manipulation and exercise in achieving clinically important but

Acknowledgements

We thank our volunteers, students, and translators. This is one review of a series conducted by the Cervical Overview Group: Bronfort G, Burnie SJ, Cameron ID, Eddy A, Ezzo J, Goldsmith CH, Graham N, Gross A, Haines T, Haraldsson B, Kay T, Kroeling P, Morien A, Peloso P, Radylovick Z, Santaguida P, Trinh K, Wang E.

References (32)

  • R. Evans et al.

    Two-year follow-up of a randomized clinical trial of spinal manipulation and two types of exercise for patients with chronic neck pain

    Spine

    (2002)
  • G.D. Giebel et al.

    Die distorsion der halswirbelsaule: Fruhfunktionalle vs. ruhigstellende behandlung

    Zentralbibliotak Chiropractic

    (1997)
  • J.L. Hoving et al.

    Manual therapy, physical therapy, or continued care by a general practitioner for patients with neck pain. A randomized controlled trial

    Annals of Internal Medicine

    (2002)
  • J.L. Hoving et al.

    Manual therapy, physical therapy, or continued care by a general practitioner for patients with neck pain: long-term results from a pragmatic randomized clinical trial

    Clinical Journal of Pain

    (2006)
  • J.L. Hoving et al.
  • G. Jull et al.

    A randomized controlled trial of exercise and manipulative therapy for cervicogenic headache

    Spine

    (2001)
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