Abstract
Purpose
We aimed to identify the risk of eating disorders (ED) in women with polycystic ovary syndrome (PCOS) compared to controls.
Methods
We performed a systematic review and meta-analysis of studies that included women with well-defined PCOS and controls and used validated ED screening/diagnostic tools to measure mean ED score, prevalence of abnormal ED scores, and/or prevalence of specific ED diagnoses such as bulimia nervosa and binge eating disorder.
Results
Eight studies, including 470 women with PCOS and 390 controls, met inclusion criteria for the systematic review. Meta-analysis of seven of those studies found that the odds of an abnormal ED score (OR 3.05; 95% CI 1.33, 6.99; four studies) and the odds of any ED diagnosis (OR 3.87; 95% CI 1.43, 10.49; four studies) were higher in women with PCOS compared to controls.
Conclusions
Our study suggests that women with PCOS are at increased odds of having abnormal ED scores and specific ED diagnoses. Given the potential implications of an ED on weight management strategies, our findings support routine screening for ED in this population.
Level of evidence
Level I, systematic review and meta-analysis.
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Funding
No specific funding was provided for this project. Laura Cooney was supported by a T32 Reproductive Training Grant.
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40519_2018_533_MOESM1_ESM.tiff
Supplementary material 1: Supp. Figure 1 Evaluation of publication bias. 1a: funnel plot for studies reporting prevalence of any eating disorder to; 1b: funnel plot for studies reporting prevalence of disordered eating (Created using Stata). (TIFF 32874 KB)
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Lee, I., Cooney, L.G., Saini, S. et al. Increased odds of disordered eating in polycystic ovary syndrome: a systematic review and meta-analysis. Eat Weight Disord 24, 787–797 (2019). https://doi.org/10.1007/s40519-018-0533-y
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DOI: https://doi.org/10.1007/s40519-018-0533-y