ABSTRACT
CONTEXT
Research suggests that pharmaceutical marketing influences prescribing and may cause cognitive dissonance for prescribers. This work has primarily been with physicians and physician–trainees. Questions remain regarding why prescribers continue to meet with pharmaceutical representatives (PRs).
OBJECTIVE
To describe the reasons that prescribers from various health professions continue to interact with PRs despite growing evidence of the influence of these interactions.
DESIGN, SETTING, AND PARTICIPANTS
Multi-disciplinary focus groups with 61 participants held in practice settings and at society meetings.
RESULTS
Most prescribers participating in our focus groups believe that overall PR interactions are beneficial to patient care and practice health. They either trust the information from PRs or feel that they are equipped to evaluate it independently. Despite acknowledgement of study findings to the contrary, prescribers state that they are able to effectively manage PR interactions such that their own prescribing is not adversely impacted. Prescribers describe few specific strategies or policies for these interactions, and report that policies are not consistently implemented with all members of a clinic or institution. Some prescribers perceive an inherent contradiction between academic centers and national societies receiving money from pharmaceutical companies, and then recommending restriction at the level of the individual prescriber. Prescribers with different training backgrounds present a few novel reasons for these meetings.
CONCLUSIONS
Despite evidence that PR detailing influences prescribing, providers from several health professions continue to believe that PR interactions improve patient care, and that they can adequately evaluate and filter information presented to them by PRs. Focus group comments suggest that cultural change is necessary to break the norms that exist in many settings. Applying policies consistently, considering non-physician members of the healthcare team, working with trainees, restructuring the current primary care model and offering convenient, individualized, non-biased educational options may aid success.
Similar content being viewed by others
REFERENCES
Peay MY, Peay ER. The role of commercial sources in the adoption of a new drug. Soc Sci Med. 1988;26(12):1183–9.
Avorn J, Chen M, Hartley R. Scientific versus commercial sources of influence on the prescribing behavior of physicians. Am J Med. 1982;73(1):4–8.
Wazana A. Physicians and the pharmaceutical industry: is a gift ever just a gift? JAMA. 2000;283(3):373–80.
Banks JW 3rd, Mainous AG 3rd. Attitudes of medical school faculty towards gifts from the pharmaceutical industry. Acad Med. 1992;67(9):610–2.
Steinman M, Shlipak M, McPhee S. Of principles and pens: attitudes and practices of medicine housestaff toward pharmaceutical industry promotions. Am J Med. 2001;110(7):551–7.
Brennan T, Rothman D, Blank L, et al. Health industry practices that create conflicts of interest: a policy proposal for academic medical centers. JAMA. 2006;294(4):429–33.
Minnigan H, Chisholm CD. Conflict of interest in the physician interface with the biomedical industry. E Med Clin N Amer. 2006;4(3):671–85.
Campo K, De Staebel O, Gijsbrechts E, van Waterschoot W. Physician’s decision process for drug prescription and the impact of pharmaceutical marketing mix instruments. Health Mark Quar. 2005;2(4):73–107.
Vainiomaki M, Helve O, Vuorenkoski L. A national survey on the effect of pharmaceutical promotion on medical students. Med Teach. 2004;6(7):630–4.
Adair RF, Holmgren LR. Do drug samples influence resident prescribing behavior? A randomized trial. Am J Med. 2005;118(8):881–4.
Crigger NJ. Pharmaceutical promotions and conflict of interest in nurse practitioner’s decision: making the undiscovered country. J Am Acad NP. 2005;17(6):207–12.
Nissen S, Wolski K. Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med. 2007;356(24):2457–71.
Rosen C. The rosiglitazone story – lessons from an FDA advisory committee meeting. N Engl J Med. 2007;357(9):844–6.
Abramson J. Overdo$ed America: The Broken Promise of American Medicine. New York: Harper Collins; 2004.
Angell M. The Truth About the Drug Companies: How They Deceive Us and What To Do About It. New York: Random House, Inc.; 2004.
Avorn J. Powerful medicines. The Benefits, Risks and Costs of Prescription Drugs. New York: Alfred a Knopf/Random House, Inc.; 2004.
Is Your Doctor Tied to Drug Makers? Editorial New York Times. July 2, 2007 www.nytimes.com/2007/07/02/opinion/02mon2.html. Accessed April 7, 2009.
Lee C. Drugmakers, Doctors Get Cozier. Washington Post. April 29, 2007; page A03. www.washingtonpost.com/wp-dyn/content/article/2007/04/28/AR2007042800896.html. Accessed April 7, 2009.
Dubner S. What Don’t We Know About the Pharmaceutical Industry? A Freakonomics Quorum. New York Times. January 24, 2008. http://freakonomics.blogs.nytimes.com/2008/01/24/what-dont-we-know-about-the-pharmaceutical-industry-a-freakonomics-quorum/. Accessed April 7, 2009.
Murphy S. Drug Sale Said Tied to Favors at Lahey. The Boston Globe. November 9, 2002. Page A1.
Steinman MA, Bero LA, Chresn M, Landefeld CS. Narrative review. The promotion of gabapentin: an analysis of internal industry documents. Ann Int Med. 2006;145(4):284–93.
Campbell EG, Gruen RL, Mountford J, Miller LG, Cleary PD, Blumenthal D. A national survey of physician-industry relationships. N Engl J Med. 2007;356(17):1742–50.
Chimonas S, Brannan TA, Rothman DJ. Physicians and drug representatives: exploring the dynamics of the relationship. J Gen Intern Med. 2007;22(2):184–90.
Sierles FS, Brodkey AC, Cleary LM, et al. Medical students’ exposure to and attitudes about drug company interactions: a national survey. JAMA. 2005;294(9):1034–42.
McKinney WP, Schiedermayer DL, Luria N, et al. Attitudes of internal medicine faculty and residents toward professional interaction with pharmaceutical sales representatives. JAMA. 1990;264(13):1693–7.
Bellin M, Mccarthy S, Drevlow L, Pierach C. Medical student’ exposure to pharmaceutical industry marketing: a survey at one U.S. medical school. Acad Med. 2004;74(11):1041–5.
Brett AS, Burr W, Moloo J. Are gifts from pharmaceutical companies ethically problematic? A survey of physicians. Arch Intern Med. 2003;163(18):2213–8.
Zipkin D, Steinman M. Interactions between PRs and doctors in training. A thematic review. J Gen Intern Med. 2005;20(8):777–86.
Jutel A, Menkes D. Soft targets: nurses and the pharmaceutical industry. PloS Med. 5(2)e5 doi:10.1371/journal.pmed.0050005.
Revised external funds policy - update from SGIM President Barbara Turner. 2006 Jan 26. http://www.sgim.org/index.cfm?section = site&pageId = 367. Accessed April 7, 2009.
Kuehn B. Pharmaceutical industry funding for residencies sparks controversy. JAMA. 2005;293:1572–80.
Academic Medical Centers Increasingly Ban Gifts from Pharmaceutical Industry. Medical News Today. http://www.medicalnewstoday.com/articles/62478.php. Accessed April 7, 2009.
AMA Opinion of the Council on Ethical and Judicial Affairs, E-8.061. http://www.mcg.edu/SOM/medicine/documents/AMAGuidelinesforIndustry.pdf. Accessed April 7, 2009.
American College of PhysiciansAmerican Society of Internal Medicine. Position Paper. Pharmacist scope of practice. Ann Intern Med. 2002;136:79–85.
Stanford School of Medicine. News Release: New Stanford Medical Center Policy Limits Drug Company Access and Gifts. 9/12/06. http://med.stanford.edu/news_releases/2006/september/coi.html. Accessed April 7, 2009.
Kowalczyk L. UMass Policy Limits Doctor, Drug Maker Ties. The Boston Globe. December 24, 2007. www.boston.com/business/healthcare/articles/2007/12/24/umass_policy_limits_doctor_drug_maker_ties/. Accessed April 7, 2009.
Yale University Policy on Conflict of Interest and Conflict of Commitment. www.yale.edu/provost/html/conflict.pdf. Accessed April 7, 2009.
Accreditation Council for Continuing Medical Education (ACCME) Standards for Commercial Support. http://www.accme.org/dir_docs/doc_upload/68b2902a-fb73–44d1–8725–80a1504e520c_uploaddocument.pdf. Accessed April 7, 2009.
Industry Funding of Medical Education: Report of an AAMC Task Force, June 2008. https://services.aamc.org/publications/showfile.cfm?file = version114.pdf&prd_id = 232&prv_id = 281&pdf_id = 114. Accessed April 7, 2009.
Hagen B, Pijl-Zieber EM, Souveny K, Lacroix A. Let’s do lunch? The ethics of accepting gifts from the pharmaceutical industry. Can Nurse. 2008;104(4):30–5.
Stokamer CL. Pharmaceutical gift giving: analysis of an ethical dilemma. J Nurs Admin. 2003;33(1):48–51.
Prosser H, Walley T. Understanding why GPs see pharmaceutical representatives: a qualitative interview study. Br J Gen Pract. 2003;53(489):305–11.
Wofford J, Ohl C. Teaching appropriate interactions with pharmaceutical company representatives: the impact of an innovative workshop on student attitudes. BMC Med Ed. 2005;5(1):5.
Cialdini R. Influence: Science and Practice 4th ed. Needham Heights, MA: Allyn & Bacon; 2001.
Agrawal S, Saluja I, Kaczorowski J. A prospective before-and-after trial of an educational intervention about pharmaceutical marketing. Acad Med. 2004;9(11):1046–50.
Anastasio G, Little JM Jr. Pharmaceutical marketing: implications for medical residency training. Pharmacother. 1996;16(1):103–7.
Vinson DC, McCandless B, Hosokawa MC. Medical students’ attitudes toward pharmaceutical marketing: possibilities for change. Fam Med. 1993;25(1):31–3.
Nelson CP, Bloom DA. Sales and science: changing patterns of pharmaceutical and medical device advertising in peer reviewed urology publications. J Urol. 2001;166(6):2317–20.
Greene J. Pharmaceutical marketing research and the prescribing physician. Ann Int Med. 2007;146:742–8.
Monaghan MS, Galt KA, Turner PD, et al. Student understanding of the relationship between the health professions and the pharmaceutical industry. TLM. 2003;15(1):14–20.
Larson K, Levy J, Rome MG, Matte TD, Silver LD, Frieden TR. Public health detailing: a strategy to improve the delivery of clinical preventive services in New York City. Pub Health Rep. 2006;121(3):228–34.
Soumerai SB, Avorn J. Principles of educational outreach (‘academic detailing’) to improve clinical decision making. JAMA. 1990;63(4):549–56.
Federation of State Medical Boards (FSMB) Research and Education Foundation Online Prescriber Education Network (OPEN) Web-based portal: Attorney General Consumer and Prescriber Education Grant Program modules available at http://www.fsmb.org/re/open/modules.html. Accessed April 7, 2009.
Consumer Reports Best Buy Drugs. http://www.consumerreports.org/health/best-buy-drugs/index.htm. Accessed April 7, 2009.
Cutrona SL, Woolhandler S, Lasser KE, Bor DH, McCormick D, Himmelstein DU. Characteristics of recipients of free prescription drug samples: a nationally representative analysis. Am J Public Health. 2008;98(2):284–9.
Spiller LD, Wymer WW Jr. Physicians’ perceptions and uses of commercial drug information sources: an examination of pharmaceutical marketing to physicians. Hlth Mark Quart. 2001;19(1):91–106.
Levy R. The role and value of pharmaceutical marketing. Arch Fam Med. 1994;3(4):327–32.
Fugh-Berman A, Ahari S. Following the script: how drug reps make friends and influence doctors. PLoS Med. 2007;4(4):e1500621–5.
Eckardt VF. Complimentary journeys to the World Congress of Gastroenterology – an inquiry of potential sponsors and beneficiaries. Zeitschr Gastro. 2000;38(1):7–11.
Krueger R, Casey M. Focus Groups 3rd ed. Thousand Oaks, CA: Sage Publications; 2000.
Prochaska JO, Velicer WF, Rossi JS, et al. Stages of change and decisional balance for 12 problem behaviors. Health Psychol. 1994;13:39–46.
Acknowledgments
We gratefully acknowledge the time and effort spent assisting with coordination and recruitment of participants from various people at the following organizations: Dartmouth Hitchcock Medical Center, Lovelace Medical Group, Nurse Practitioner Associates for Continuing Education (NPACE), Physician Assistant Academy of VT (PAAV), UMMHC Community Medical Group, and UMMS Clinical Faculty Development Center.
Funding/Support
This work was funded by the Attorney General Consumer and Prescriber Grants Program.
Role of the Sponsors
The funder had no role in the design and conduct of the study; collection, management, analysis, and interpretation of the data; and preparation, review, or approval of the manuscript.
Author Contributions
Dr. Fischer had full access to all the data in the study and takes responsibility for the integrity of the data and the accuracy of the analysis.
Study concept and design: Fischer, Keough, Mazor, Baril, Gurwitz.
Acquisition of data: Fischer, Keough, Saccoccio, Von Worley.
Analysis and interpretation of data: Fischer, Mazor, Keough, Baril, Ladd.
Drafting of the manuscript: Fischer, Keough.
Critical revision of the manuscript for important intellectual content: Fischer, Keough, Baril, Saccoccio, Mazor, Ladd, Von Worley, Gurwitz.
Statistical analysis: Fischer, Baril.
Administrative, technical, or material support: Keough, Baril, Saccoccio, Von Worley.
Study supervision: Fischer, Keough, Gurwitz.
Other (qualitative methodology): Mazor, Ladd.
Financial Disclosures and Conflicts of Interest
None disclosed.
Author information
Authors and Affiliations
Corresponding author
Additional information
This work was funded by the Attorney General Consumer and Prescriber Grants Program.
Appendix: Focus Group Questions
Appendix: Focus Group Questions
1. | How do you learn new information or maintain your knowledge of pharmaceuticals? By this I mean new drugs, new indications for established drugs, new side effect or risk information? |
2. | Please tell me about your exposure to drug marketing in the last week? Please be specific. Pharmaceutical representatives (called drug reps)? Journal advertising? DTC ads on TV/radio? Patient requests? Professional meetings? Educational presentations? Others? If there is little discussion probe - how about in the last month? |
3. | Overall do you feel that interactions with drug reps help or hurt your patient care? Can you give specific examples? Why? How? |
4. | What aspects of drug marketing, if any, do you find helpful, useful or informative? Why? How? |
5. | What aspects of drug marketing, if any, do you personally find difficult to deal with? Why? How? |
6. | Have you developed any particular strategies for dealing with drug marketing techniques that you have found helpful? Please be specific. How did you learn this technique? If they don’t come up probe: drug reps, DTC advertising, how about here at the conference? |
7. | What sort of training or other support (including print or Web resources) would you need to better manage your interactions with drug reps or other pharmaceutical marketing? |
8. | Please tell me about any workplace policies that regulate your interactions with pharmaceutical representatives? What are those policies? Are they enforced? How? How do they impact your interactions with representatives? Patient care? Overall do you feel they are helpful? Harmful? What else might you suggest? |
9. | Any other information you would like to share on this topic? |
10. | What do you think about the fact that drug reps can obtain data about your own prescribing habits? Have you ever received personal information about your own prescribing from a pharmaceutical representative? What impact did that have on your interaction? On your prescribing? |
11. | When a choice exists, how do you decide to prescribe generic or prescription medication? |
12. | Now I’d like you to think about any personal information you may have received from a pharmacist or health plan about formulary medications, prescribing or generic medications. What impact did that have on your prescribing? |
13. | Can you talk about what happens when patients request specific medications based ads they have seen? What’s a typical interaction like when this occurs? Do you feel these patients share any characteristics? (e.g., age, sex, SES, health status, conditions, etc.) |
14. | Please tell me about any HARD experiences you have had with a patient requesting a drug after seeing ads for it. What was most difficult? |
15. | Please tell me about any experiences you have had where a patient requested a drug because of an ad which led to better care for the patient. |
16. | How do you usually respond to a patient’s request for medications that are not clinically appropriate? What influences how you respond to these sorts of requests? |
17. | Have you ever had training in how to respond to patient requests for specific advertised medications? What specific areas do you think such training should cover? |
18. | What other support (including Web or print resources) would be helpful to you? |
Rights and permissions
About this article
Cite this article
Fischer, M.A., Keough, M.E., Baril, J.L. et al. Prescribers and Pharmaceutical Representatives: Why Are We Still Meeting?. J GEN INTERN MED 24, 795–801 (2009). https://doi.org/10.1007/s11606-009-0989-6
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11606-009-0989-6