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Cardiovascular Disease Prevention in Women

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Book cover ASPC Manual of Preventive Cardiology

Part of the book series: Contemporary Cardiology ((CONCARD))

Abstract

Cardiovascular diseases remain the leading cause of morbidity and mortality among women worldwide. The differences in the pathophysiological basis of cardiovascular health among men and women result in variable cardiovascular response to cardiovascular risk factors. Women remain underrepresented in clinical trials, and this has led to lack of sex-specific analysis of clinical trial data and often lack of evidence related to sex-specific recommendations for atherosclerotic cardiovascular disease (ASCVD) prevention in women. To date, there remains sex-specific risk factor assessment tool. Nonetheless, in addition to traditional ASCVD risk factors, some that affect women differently than men, there are female-specific and female-predominant ASCVD risk factors that should be assessed when applying primary prevention strategies in women. There is a lack of awareness of these sex differences in ASCVD risk assessment and particularly of the female-specific risk factors. Nonetheless, this should be part of any ASCVD risk assessment in women. In this chapter, we aim to describe the sex differences in traditional ASCVD risk factors and describe the female-specific and female-predominant ASCVD risk factors and how to incorporate this information into risk assessment and primary preventive strategies in women.

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References

  1. Campia U, Moslehi JJ, Amiri-Kordestani L, et al. Cardio-oncology: vascular and metabolic perspectives: a scientific statement from the American Heart Association. Circulation. 2019;139:e579–602.

    Article  PubMed  PubMed Central  Google Scholar 

  2. Virani SS, Alonso A, Benjamin EJ, et al. Heart disease and stroke Statistics-2020 update: a report from the American Heart Association. Circulation. 2020;141:CIR0000000000000757.

    Article  Google Scholar 

  3. Benjamin EJ, Muntner P, Alonso A, et al. Heart disease and stroke statistics-2019 update: a report from the American Heart Association. Circulation. 2019;139:e56–e528.

    Article  PubMed  Google Scholar 

  4. Mosca L, Benjamin EJ, Berra K, et al. Effectiveness-based guidelines for the prevention of cardiovascular disease in women—2011 update. Circulation. 2011;123:1243–62.

    Article  PubMed  PubMed Central  Google Scholar 

  5. Gulati M. Improving the cardiovascular health of women in the nation. Circulation. 2017;135:495–8.

    Article  PubMed  Google Scholar 

  6. Kim ESH, Menon V. Status of women in cardiovascular clinical trials. Arterioscler Thromb Vasc Biol. 2009;29:279–83.

    Article  CAS  PubMed  Google Scholar 

  7. Bairey Merz CN, Andersen H, Sprague E, et al. Knowledge, attitudes, and beliefs regarding cardiovascular disease in women. J Am Coll Cardiol. 2017;70:123–32.

    Article  PubMed  Google Scholar 

  8. Nanna MG, Wang TY, Xiang Q, et al. Sex differences in the use of statins in community practice. Circ Cardiovasc Qual Outcomes. 2019;12:e005562.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Brown HL, Warner JJ, Gianos E, et al. Promoting risk identification and reduction of cardiovascular disease in women through collaboration with obstetricians and gynecologists: a presidential advisory from the American Heart Association and the American College of Obstetricians and Gynecologists. Circulation. 2018;137:e843–52.

    Article  PubMed  Google Scholar 

  10. Reynolds HR, Srichai MB, Iqbal SN, et al. Mechanisms of myocardial infarction in women without angiographically obstructive coronary artery disease. Circulation. 2011;124:1414–25.

    Article  PubMed  PubMed Central  Google Scholar 

  11. CDC. Prevalence of obesity and severe obesity among adults: United States, 2017–2018; 2020.

    Google Scholar 

  12. Chomistek AK, Manson JE, Stefanick ML, et al. Relationship of sedentary behavior and physical activity to incident cardiovascular disease: results from the Women’s Health Initiative. J Am Coll Cardiol. 2013;61:2346–54.

    Article  PubMed  PubMed Central  Google Scholar 

  13. Armstrong ME, Green J, Reeves GK, Beral V, Cairns BJ. Frequent physical activity may not reduce vascular disease risk as much as moderate activity: large prospective study of women in the United Kingdom. Circulation. 2015;131:721–9.

    Article  CAS  PubMed  Google Scholar 

  14. Arnett DK, Blumenthal RS, Albert MA, et al. 2019 ACC/AHA guideline on the primary prevention of cardiovascular disease: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Circulation. 2019;140:e596–646.

    PubMed  PubMed Central  Google Scholar 

  15. Huxley RR, Woodward M. Cigarette smoking as a risk factor for coronary heart disease in women compared with men: a systematic review and meta-analysis of prospective cohort studies. Lancet (London, England). 2011;378:1297–305.

    Article  Google Scholar 

  16. Hu FB, Stampfer MJ, Manson JE, et al. Trends in the incidence of coronary heart disease and changes in diet and lifestyle in women. N Engl J Med. 2000;343:530–7.

    Article  CAS  PubMed  Google Scholar 

  17. McKee SA, Smith PH, Kaufman M, Mazure CM, Weinberger AH. Sex differences in varenicline efficacy for smoking cessation: a meta-analysis. Nicotine Tob Res. 2016;18:1002–11.

    Article  PubMed  Google Scholar 

  18. Wenger NK, Arnold A, Bairey Merz CN, et al. Hypertension across a woman’s life cycle. J Am Coll Cardiol. 2018;71:1797–813.

    Article  PubMed  PubMed Central  Google Scholar 

  19. Lloyd-Jones DM, Evans JC, Levy D. Hypertension in adults across the age spectrum: current outcomes and control in the community. JAMA. 2005;294:466–72.

    Article  CAS  PubMed  Google Scholar 

  20. Fryar CD, Ostchega Y, Hales CM, Zhang G, Kruszon-Moran D. Hypertension prevalence and control among adults: United States, 2015–2016. NCHS Data Brief. 2017;(289):1–8.

    Google Scholar 

  21. Ji H, Kim A, Ebinger JE, et al. Sex Differences in Blood Pressure Trajectories Over the Life Course [published correction appears in JAMA Cardiol. 2020;5(3):364]. JAMA Cardiol. 2020;5(3):19–26. https://doi.org/10.1001/jamacardio.2019.5306.

  22. Graham I, Cooney MT, Bradley D, Dudina A, Reiner Z. Dyslipidemias in the prevention of cardiovascular disease: risks and causality. Curr Cardiol Rep. 2012;14(6):709–20. https://doi.org/10.1007/s11886-012-0313-7.

  23. Cooney MT, Dudina A, De Bacquer D, et al. HDL cholesterol protects against cardiovascular disease in both genders, at all ages and at all levels of risk. Atherosclerosis. 2009;206:611–6.

    Article  CAS  PubMed  Google Scholar 

  24. Bittner V, Johnson BD, Zineh I, et al. The triglyceride/high-density lipoprotein cholesterol ratio predicts all-cause mortality in women with suspected myocardial ischemia: a report from the Women’s Ischemia Syndrome Evaluation (WISE). Am Heart J. 2009;157:548–55.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  25. Carroll MD, Fryar CD, Nguyen DT. Total and High-density Lipoprotein Cholesterol in Adults: United States, 2015-2016. NCHS Data Brief. 2017;(290):1–8.

    Google Scholar 

  26. Mora S, Buring JE, Ridker PM, Cui Y. Association of high-density lipoprotein cholesterol with incident cardiovascular events in women, by low-density lipoprotein cholesterol and apolipoprotein B100 levels: a cohort study. Ann Intern Med. 2011;155:742–50.

    Article  PubMed  PubMed Central  Google Scholar 

  27. Parris ES, Lawrence DB, Mohn LA, Long LB. Adherence to statin therapy and LDL cholesterol goal attainment by patients with diabetes and dyslipidemia. Diabetes Care. 2005;28:595–9.

    Article  CAS  PubMed  Google Scholar 

  28. Safford MM, Gamboa CM, Durant RW, et al. Race-sex differences in the management of hyperlipidemia: the REasons for Geographic and Racial Differences in Stroke study. Am J Prev Med. 2015;48:520–7.

    Article  PubMed  PubMed Central  Google Scholar 

  29. Kostis WJ, Cheng JQ, Dobrzynski JM, Cabrera J, Kostis JB. Meta-analysis of statin effects in women versus men. J Am Coll Cardiol. 2012;59:572–82.

    Article  CAS  PubMed  Google Scholar 

  30. Fulcher J, O’Connell R, Voysey M, et al. Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials. Lancet (London, England). 2015;385:1397–405.

    Article  CAS  Google Scholar 

  31. Matsushita K, Blecker S, Pazin-Filho A, et al. The association of hemoglobin A1C with incident heart failure among people without diabetes: the Atherosclerosis Risk in Communities study. Diabetes. 2010;59:2020–6.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  32. Emerging Risk Factors Collaboration. Glycated hemoglobin measurement and prediction of cardiovascular disease. JAMA. 2014;311:1225–33.

    Article  CAS  Google Scholar 

  33. Selvin E, Lazo M, Chen Y, et al. Diabetes mellitus, prediabetes, and incidence of subclinical myocardial damage. Circulation. 2014;130:1374–82.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  34. Selvin E, Steffes MW, Zhu H, et al. Glycated hemoglobin, diabetes, and cardiovascular risk in nondiabetic adults. N Engl J Med. 2010;362:800–11.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  35. Peters SAE, Huxley RR, Woodward M. Diabetes as risk factor for incident coronary heart disease in women compared with men: a systematic review and meta-analysis of 64 cohorts including 858,507 individuals and 28,203 coronary events. Diabetologia. 2014;57:1542–51.

    Article  PubMed  Google Scholar 

  36. Peters SAE, Huxley RR, Woodward M. Diabetes as a risk factor for stroke in women compared with men: a systematic review and meta-analysis of 64 cohorts, including 775,385 individuals and 12,539 strokes. Lancet (London, England). 2014;383:1973–80.

    Article  Google Scholar 

  37. Wexler DJ, Grant RW, Meigs JB, Nathan DM, Cagliero E. Sex disparities in treatment of cardiac risk factors in patients with type 2 diabetes. Diabetes Care. 2005;28:514–20.

    Article  PubMed  Google Scholar 

  38. Saeed A, Ballantyne CM. Assessing cardiovascular risk and testing in type 2 diabetes. Curr Cardiol Rep. 2017;19:19.

    Article  PubMed  Google Scholar 

  39. ADVANCE Collaborative Group. Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. N Engl J Med. 2008;358:2560–72.

    Article  Google Scholar 

  40. Duckworth W, Abraira C, Moritz T, et al. Glucose control and vascular complications in veterans with type 2 diabetes. N Engl J Med. 2009;360:129–39.

    Article  CAS  PubMed  Google Scholar 

  41. Grundy SM, Stone NJ, Bailey AL, et al. AHA/ACC/AACVPR/AAPA/ABC/ACPM/ADA/AGS/APhA/ASPC/NLA/PCNA Guideline on the Management of Blood Cholesterol: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines [published correction appears in Circulation. 2019 Jun 18;139(25):e1182–e1186]. Circulation. 2019;139(25):e1082–e1143. https://doi.org/10.1161/CIR.0000000000000625.

  42. Ferranti EP, Jones EJ, Hernandez TL. Pregnancy reveals evolving risk for cardiometabolic disease in women. J Obstet Gynecol Neonatal Nurs. 2016;45:413–25.

    Article  PubMed  Google Scholar 

  43. Brown MC, Best KE, Pearce MS, Waugh J, Robson SC, Bell R. Cardiovascular disease risk in women with pre-eclampsia: systematic review and meta-analysis. Eur J Epidemiol. 2013;28:1–19.

    Article  PubMed  Google Scholar 

  44. Grandi SM, Vallée-Pouliot K, Reynier P, et al. Hypertensive disorders in pregnancy and the risk of subsequent cardiovascular disease. Paediatr Perinat Epidemiol. 2017;31:412–21.

    Article  PubMed  Google Scholar 

  45. Bellamy L, Casas J-P, Hingorani AD, Williams DJ. Pre-eclampsia and risk of cardiovascular disease and cancer in later life: systematic review and meta-analysis. BMJ (Clinical research ed). 2007;335:974.

    Article  Google Scholar 

  46. Berman DS, Wong ND, Gransar H, et al. Relationship between stress-induced myocardial ischemia and atherosclerosis measured by coronary calcium tomography. J Am Coll Cardiol. 2004;44:923–30.

    Article  CAS  PubMed  Google Scholar 

  47. Hauspurg A, Countouris ME, Jeyabalan A, et al. Risk of hypertension and abnormal biomarkers in the first year postpartum associated with hypertensive disorders of pregnancy among overweight and obese women. Pregnancy Hypertens. 2019;15:1–6.

    Article  PubMed  Google Scholar 

  48. Garcia M, Mulvagh SL, Merz CN, Buring JE, Manson JE. Cardiovascular disease in women: clinical perspectives. Circ Res. 2016;118:1273–93.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  49. McDonald SD, Malinowski A, Zhou Q, Yusuf S, Devereaux PJ. Cardiovascular sequelae of preeclampsia/eclampsia: a systematic review and meta-analyses. Am Heart J. 2008;156:918–30.

    Article  PubMed  Google Scholar 

  50. American College of Obstetricians, Gynecologists, Task Force on Hypertension in Pregnancy. Hypertension in pregnancy. Report of the American College of Obstetricians and Gynecologists’ Task Force on Hypertension in Pregnancy. Obstet Gynecol. 2013;122:1122–31.

    Google Scholar 

  51. Mongraw-Chaffin ML, Cirillo PM, Cohn BA. Preeclampsia and cardiovascular disease death: prospective evidence from the child health and development studies cohort. Hypertension (Dallas, Tex: 1979). 2010;56:166–71.

    Article  CAS  Google Scholar 

  52. Leon LJ, McCarthy FP, Direk K, et al. Preeclampsia and cardiovascular disease in a large UK pregnancy cohort of linked electronic health records: a CALIBER study. Circulation. 2019;140:1050–60.

    Article  PubMed  Google Scholar 

  53. ACOG Committee Opinion No. 736: optimizing postpartum care. Obstet Gynecol. 2018;131:e140–e150.

    Google Scholar 

  54. Kim C, Newton KM, Knopp RH. Gestational diabetes and the incidence of type 2 diabetes: a systematic review. Diabetes Care. 2002;25:1862–8.

    Article  PubMed  Google Scholar 

  55. Kramer CK, Campbell S, Retnakaran R. Gestational diabetes and the risk of cardiovascular disease in women: a systematic review and meta-analysis. Diabetologia. 2019;62:905–14.

    Article  PubMed  Google Scholar 

  56. Carr DB, Utzschneider KM, Hull RL, et al. Gestational diabetes mellitus increases the risk of cardiovascular disease in women with a family history of type 2 diabetes. Diabetes Care. 2006;29:2078–83.

    Article  PubMed  Google Scholar 

  57. Shah BR, Retnakaran R, Booth GL. Increased risk of cardiovascular disease in young women following gestational diabetes mellitus. Diabetes Care. 2008;31:1668–9.

    Article  PubMed  PubMed Central  Google Scholar 

  58. Daly B, Toulis KA, Thomas N, et al. Increased risk of ischemic heart disease, hypertension, and type 2 diabetes in women with previous gestational diabetes mellitus, a target group in general practice for preventive interventions: a population-based cohort study. PLoS Med. 2018;15:–e1002488.

    Google Scholar 

  59. Retnakaran R, Ye C, Hanley AJ, Connelly PW, Sermer M, Zinman B. Screening glucose challenge test in pregnancy can identify women with an adverse postpartum cardiovascular risk factor profile: implications for cardiovascular risk reduction. J Am Heart Assoc. 2019;8:e014231.

    Article  PubMed  PubMed Central  Google Scholar 

  60. Goueslard K, Cottenet J, Mariet AS, et al. Early cardiovascular events in women with a history of gestational diabetes mellitus. Cardiovasc Diabetol. 2016;15:15.

    Article  PubMed  PubMed Central  Google Scholar 

  61. Tanz LJ, Stuart JJ, Williams PL, et al. Preterm delivery and maternal cardiovascular disease in young and middle-aged adult women. Circulation. 2017;135:578–89.

    Article  PubMed  PubMed Central  Google Scholar 

  62. Minissian MB, Kilpatrick S, Eastwood JA, et al. Association of spontaneous preterm delivery and future maternal cardiovascular disease. Circulation. 2018;137:865–71.

    Article  PubMed  PubMed Central  Google Scholar 

  63. Catov JM, Snyder GG, Bullen BL, Barinas-Mitchell EJM, Holzman C. Women with preterm birth have evidence of subclinical atherosclerosis a decade after delivery. J Womens Health (2002). 2019;28:621–7.

    Article  Google Scholar 

  64. Tanz LJ, Stuart JJ, Williams PL, et al. Preterm delivery and maternal cardiovascular disease risk factors: the nurses’ health study II. J Womens Health (2002). 2019;28:677–85.

    Article  Google Scholar 

  65. Wu P, Gulati M, Kwok CS, et al. Preterm delivery and future risk of maternal cardiovascular disease: a systematic review and meta-analysis. J Am Heart Assoc. 2018;7:e007809.

    Article  PubMed  PubMed Central  Google Scholar 

  66. Muka T, Oliver-Williams C, Kunutsor S, et al. Association of age at onset of menopause and time since onset of menopause with cardiovascular outcomes, intermediate vascular traits, and all-cause mortality: a systematic review and meta-analysis. JAMA Cardiol. 2016;1:767–76.

    Article  PubMed  Google Scholar 

  67. Christ J, Gunning M, Palla G, et al. Prolonged estrogen deprivation is associated with increased cardiovascular disease risk among women with primary ovarian insufficiency. Fertil Steril. 2017;108:e392.

    Article  Google Scholar 

  68. Daan NMP, Muka T, Koster MPH, et al. Cardiovascular risk in women with premature ovarian insufficiency compared to premenopausal women at middle age. J Clin Endocrinol Metabol. 2016;101:3306–15.

    Article  CAS  Google Scholar 

  69. Roeters van Lennep JE, Heida KY, Bots ML, Hoek A, collaborators of the Dutch Multidisciplinary Guideline Development Group on Cardiovascular Risk Management after Reproductive Disorders. Cardiovascular disease risk in women with premature ovarian insufficiency: a systematic review and meta-analysis. Eur J Prev Cardiol. 2016;23:178–86.

    Article  PubMed  Google Scholar 

  70. Rossouw JE, Anderson GL, Prentice RL, et al. Risks and benefits of estrogen plus progestin in healthy postmenopausal women: principal results from the Women’s Health Initiative randomized controlled trial. JAMA. 2002;288:321–33.

    Article  CAS  PubMed  Google Scholar 

  71. Grady D, Herrington D, Bittner V, et al. Cardiovascular disease outcomes during 6.8 years of hormone therapy: Heart and Estrogen/progestin Replacement Study follow-up (HERS II). JAMA. 2002;288:49–57.

    Article  PubMed  Google Scholar 

  72. Hulley S, Grady D, Bush T, et al. Randomized trial of estrogen plus progestin for secondary prevention of coronary heart disease in postmenopausal women. Heart and Estrogen/progestin Replacement Study (HERS) Research Group. JAMA. 1998;280:605–13.

    Article  CAS  PubMed  Google Scholar 

  73. Udell JA, Lu H, Redelmeier DA. Long-term cardiovascular risk in women prescribed fertility therapy. J Am Coll Cardiol. 2013;62:1704–12.

    Article  PubMed  Google Scholar 

  74. Udell JA, Lu H, Redelmeier DA. Failure of fertility therapy and subsequent adverse cardiovascular events. CMAJ/journal de l’Association medicale canadienne. 2017;189:E391–7.

    Article  PubMed  Google Scholar 

  75. Shufelt CL, Bairey Merz CN. Contraceptive hormone use and cardiovascular disease. J Am Coll Cardiol. 2009;53:221–31.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  76. Sokka T, Toloza S, Cutolo M, et al. Women, men, and rheumatoid arthritis: analyses of disease activity, disease characteristics, and treatments in the QUEST-RA study. Arthritis Res Ther. 2009;11:R7.

    PubMed  PubMed Central  Google Scholar 

  77. del Rincon I, Polak JF, O’Leary DH, et al. Systemic inflammation and cardiovascular risk factors predict rapid progression of atherosclerosis in rheumatoid arthritis. Ann Rheum Dis. 2015;74:1118–23.

    Article  PubMed  CAS  Google Scholar 

  78. Mehta LS, Watson KE, Barac A, et al. Cardiovascular disease and breast cancer: where these entities intersect: a scientific statement from the American Heart Association. Circulation. 2018;137:e30–66.

    Article  PubMed  PubMed Central  Google Scholar 

  79. Gulati M, Mulvagh SL. The connection between the breast and heart in a woman: breast cancer and cardiovascular disease. Clin Cardiol. 2018;41:253–7.

    Article  PubMed  PubMed Central  Google Scholar 

  80. Saeed A. Prevention of cardiovascular disease in women. Methodist Debakey Cardiovasc J. 2017;13:179–262.

    Google Scholar 

  81. Cardinale D, Colombo A, Lamantia G, et al. Anthracycline-induced cardiomyopathy: clinical relevance and response to pharmacologic therapy. J Am Coll Cardiol. 2010;55:213–20.

    Article  CAS  PubMed  Google Scholar 

  82. Dang CT, Yu AF, Jones LW, et al. Cardiac surveillance guidelines for trastuzumab-containing therapy in early-stage breast cancer: getting to the heart of the matter. J Clin Oncol. 2016;34:1030–3.

    Article  PubMed  PubMed Central  CAS  Google Scholar 

  83. Hooning MJ, Botma A, Aleman BMP, et al. Long-term risk of cardiovascular disease in 10-year survivors of breast cancer. J Natl Cancer Inst. 2007;99:365–75.

    Article  PubMed  Google Scholar 

  84. Doyle JJ, Neugut AI, Jacobson JS, et al. Radiation therapy, cardiac risk factors, and cardiac toxicity in early-stage breast cancer patients. Int J Radiat Oncol Biol Phys. 2007;68:82–93.

    Article  PubMed  Google Scholar 

  85. Giordano SH, Kuo Y-F, Freeman JL, Buchholz TA, Hortobagyi GN, Goodwin JS. Risk of cardiac death after adjuvant radiotherapy for breast cancer. J Natl Cancer Inst. 2005;97:419–24.

    Article  PubMed  PubMed Central  Google Scholar 

  86. Cardiology ACo. ASCVD risk estimator plus calculator. Retrieved from: http://tools.acc.org/ASCVD-Risk-Estimator-Plus/#!/calculate/estimate/.

  87. Greenland P, Alpert JS, Beller GA, et al. 2010 ACCF/AHA guideline for assessment of cardiovascular risk in asymptomatic adults: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2010;56:e50–103.

    Article  PubMed  Google Scholar 

  88. Bigeh A, Shekar C, Gulati M. Sex differences in coronary artery calcium and long-term CV mortality. Curr Cardiol Rep. 2020;22:21.

    Article  PubMed  Google Scholar 

  89. Nasir K, McClelland RL, Blumenthal RS, et al. Coronary artery calcium in relation to initiation and continuation of cardiovascular preventive medications: the Multi-Ethnic Study of Atherosclerosis (MESA). Circ Cardiovasc Qual Outcomes. 2010;3:228–35.

    Article  PubMed  PubMed Central  Google Scholar 

  90. Agarwala A, Michos ED, Samad Z, Ballantyne CM, Virani SS. The use of sex-specific factors in the assessment of women’s cardiovascular risk. Circulation. 2020;141:592–9.

    Article  PubMed  Google Scholar 

  91. Lloyd-Jones DM, Hong Y, Labarthe D, et al. Defining and setting national goals for cardiovascular health promotion and disease reduction. Circulation. 2010;121:586–613.

    Article  PubMed  Google Scholar 

  92. Lundberg GP, Mehta LS, Sanghani RM, et al. Heart centers for women. Circulation. 2018;138:1155–65.

    Article  PubMed  Google Scholar 

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Authors and Affiliations

  1. Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, USA

    Anum Saeed

  2. Division of Cardiology, University of Arizona College of Medicine, Phoenix, AZ, USA

    Martha Gulati

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  1. Anum Saeed
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  2. Martha Gulati
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Editors and Affiliations

  1. Heart Disease Prevention Program, Division of Cardiology, University of California, Irvine, Irvine, CA, USA

    Nathan D. Wong

  2. Division of Cardiovascular Medicine, University of California, Davis, Sacramento, CA, USA

    Ezra A. Amsterdam

  3. Cicarrone Center for the Prevention of Cardiovascular Disease, John Hopkins University School of Medicine, Baltimore, MD, USA

    Peter P. Toth

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Saeed, A., Gulati, M. (2021). Cardiovascular Disease Prevention in Women. In: Wong, N.D., Amsterdam, E.A., Toth, P.P. (eds) ASPC Manual of Preventive Cardiology. Contemporary Cardiology. Springer, Cham. https://doi.org/10.1007/978-3-030-56279-3_19

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