Table 1. Patient characteristics of 394 individuals with an elevated natriuretic peptide level, subdivided in those referred and those not referred for echocardiography
Referred n = 166Not referred n = 228P value
Median age in years (IQR)73±21.878±17.3<0.001
Median NT-proBNP in pg/ml (IQR)400.0±348.0219.0±193.80.104
Median BNP in pg/ml (IQR)83.0±86.063.0±83.0<0.001
Female121 (72.9)150 (65.8)0.164
Mean BMI in kg/m2 (SD) (n = 320)29.7±6.728.1±5.20.024
Mean SBP in mmHg (SD) (n = 385)135.3±17.5135.2±19.30.938
Mean DBP in mmHg (SD) (n = 385)80.3±12.178.6±10.90.154
Smoking ( n = 307), n (%)
Never
Past
Current
68 (52.7)
50 (38.8)
11 (8.5)
90 (50.6)
76 (42.7)
12 (6.7)
0.798
0.566
0.714
Comorbidities n (%)
Anaemia24 (14.5)35 (15.4)0.919
Angina pectoris22 (13.3)27 (11.8)0.791
Prior myocardial infarction10 (6.0)34 (14.9)0.009
PCI or CABG9 (5.4)11 (4.8)0.972
Atrial fibrillation34 (20.5)51 (22.4)0.745
Valvular heart disease16 (9.6)21 (9.2)1.00
Hypertension95 (57.2)129 (56.6)0.980
COPD14 (8.4)33 (14.5)0.095
Type 2 diabetes37 (22.3)53 (23.2)0.919
Dyslipidaemia30 (18.1)39 (17.1)0.908
Chronic kidney disease36 (21.7)63 (27.6)0.220
Participation in integrated PC disease management programme n (%)
Total103 (62.0)153 (67.1)0.351
COPD programme7 (4.2)14 (6.1)0.540
Type 2 diabetes programme32 (19.3)50 (21.9)0.607
CVRM programme69 (41.6)101 (44.3)0.662
Blood test values n (%)
eGFR<60 ml/min/1.73 m2 (n = 388)32 (19.9)60 (26.4)0.169
HF suggestive symptoms
Shortness of breath92 (55.4)105 (46.1)0.083
Reduced exercise tolerance and/or fatigue74 (44.6)75 (32.9)0.024
Orthopnoea and/or nocturnal dyspnoea19 (11.4)14 (6.1)0.090
Nocturia21 (12.7)28 (12.3)1.00
Peripheral oedema68 (41.0)90 (39.5)0.846
HF suggestive signs
Pulmonary crackles24 (14.5)26 (11.4)0.456
Peripheral oedema53 (31.9)73 (32.0)1.00
  • Data presented as mean±standard deviation (SD), median±interquartile range (IQR), or absolute count (%). BMI = body mass index. CABG = coronary artery bypass graft surgery. COPD = chronic obstructive pulmonary disease. CVRM = cardiovascular risk management. DBP = diastolic blood pressure. eGFR = estimated glomerular filtration rate. HF = heart failure. NT-proBNP = N-terminal pro-B-type natriuretic peptide. PC = primary care. PCI = percutaneous coronary intervention. SBP = systolic blood pressure.