Table 1. First-choice treatment changes over time
20122013201420152016201720182019TotalConfidence interval of linear regression
n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%)
Pivmecillinam9583 (50.9%)9687 (53.6%)9579 (51.9%)9881 (52.9%)9923 (53.3%)9706 (53.6%)9712 (51.9%)10 074 (52.6%)78 145 (52.5%)-0.1% (-0.2% to 0.5%)
Trimethoprim2871 (15.3%)2554 (14.0%)2608 (14.2%)2473 (13.2%)2570 (13.8%)2490 (13.7%)2128 (11.4%)2124 (11.1%)19 818 (13.2%)-0.5% (-0.7% to 0.2%)
Nitrofurantoin1019 (5.4%)895 (5.0%)872 (4.7%)940 (5.0%)968 (5.2%)998 (5.5%)841 (4.5%)1046 (5.5%)7579 (5.1%)0.0% (-0.1% to 0.1%)
Trimethoprim– sulfamethoxazole1717 (9.1%)1695 (9.4%)2163 (11.8%)2307 (12.4%)2497 (13.5%)2659 (14.7%)3823 (20.4%)4019 (21.0%)20 880 (14.0%)1.8% (1.2% to 2.3%)
Fluoroquinolones2614 (13.9%)2403 (13.3%)2399 (13.0%)2218 (11.9%)1917 (10.3%)1559 (8.6%)1458 (7.8%)1136 (5.9%)15 704 (10.9%)-1.1% (-1.4% to 0.9%)
Other1021 (5.4%)844 (4.7%)817 (4.4%)859 (4.6%)725 (3.9%)710 (3.9%)739 (4.0%)750 (3.9%)6465 (4.3%)-0.2% (-0.3% to 0.1%)
Total18 869 (100%)18 078 (100%)18 438 (100%)18 678 (100%)18 600 (100%)18 122 (100%)18 701 (100%)19 149 (100%)148 6350.003% (-0.005% to 0.01%)
Narrow-spectrum antibiotics13 517 (71.6%)13 136 (72.7%)13 059 (70.8%)13 294 (71.2%)13 461 (72.3%)13 194 (72.8%)12 681 (67.8%)13 244 (69.2%)105 586 (71.0%)-0.2% (-1.0% to 0.2%)
Broad-spectrum antibiotics5352 (28.4%)4942 (27.3%)5379 (29.2%)5384 (28.8%)5139 (27.7%)4928 (27.2%)6020 (32.2%)5905 (30.8%)41 597 (28.0%)0.4% (-0.2% to 1.0%)