Table 4. Cascade effects within 6 months after testing using two or more analytes simultaneously^a

	Mean number of consultations per person^b (95% CI)	Mean number of referrals per person (95% CI)	Mean number of total blood tests requested (95% CI)	Mean number of appointments for blood testing in 6 months (95% CI)
True-positive(n = 95)	12.4 (10.5 to 14.3)^c	1.6 (1.2 to 2.0)^c	51 (36.9 to 65.1)^c	4.7 (3.7 to 5.7)^c
False-negative(n = 60)	10.3 (8.7 to 11.9)^c	1.4 (0.8 to 2.0)^c	33 (22.5 to 43.5)^c	3.8 (2.9 to 4.7)^c
False-positive(n = 7823)	10.5 (10.2 to 10.7)^c	0.7 (0.6 to 0.7)^c	29.8 (28.8 to 30.8)^c	3.1 (3.0 to 3.2)^c
True-negative(n = 22 022)	8.6 (8.5 to 8.7)^c	0.6 (0.5 to 0.6)^c	19.8 (19.3 to 20.2)^c	2.3 (2.2 to 2.3)^c

^aLFT panel of more than one analyte that is defined as abnormal if any of the analytes not within the reference range. True-positives are patients with a positive test who develop target condition. False-positives are patients with a positive test without target condition. False-negatives are patients with a negative test who develop target condition. True-negatives are people with a negative test with no relevant disease. ^bIncludes face-to-face consultations, home visits, and telephone consultations. ^c P<0.001, comparing true-positives to false-negatives and false-positives to true-negatives