| Characteristic | Total cohort, n (%)a,b |
|---|---|
| Participants | 277 (100) |
| Age, years, median (IQR) | 73 (68–78) |
| Sex | |
| Male | 152 (54.9) |
| Female | 125 (45.1) |
| Ethnic group | |
| White | 269 (97.1) |
| Asian | 5 (1.8) |
| Black | 2 (0.7) |
| Mixed | 1 (0.4) |
| Smoking status | |
| Non-smoker | 133 (48.0) |
| Ex-smoker | 136 (49.1) |
| Current | 8 (2.9) |
| BMI, kg/m2, median (IQR) | 27.6 (24.5–30.4) |
| Asthma | 20 (7.2) |
| COPD | 16 (5.8) |
| Inhaled steroids | 12 (4.3) |
| Atrial fibrillation | 39 (14.1) |
| Diabetes | 38 (13.7) |
| Hyperlipidaemia | 134 (48.4) |
| Hypertension | 149 (53.8) |
| Myocardial infarct | 12 (4.3) |
| PCI | 11 (4.0) |
| CABG | 5 (1.8) |
| Chronic kidney disease | 35 (12.6) |
| NYHA class | |
| I | 178 (64.3) |
| II | 89 (32.1) |
| III | 10 (3.6) |
| Socioeconomic class | |
| 1 (least deprived) | 67 (24.2) |
| 2 | 65 (23.5) |
| 3 | 85 (30.7) |
| 4 | 36 (13.0) |
| 5 (most deprived) | 21 (7.6) |
| Missing | 3 (1.1) |
| Ejection fraction, %, median (IQR) | 69 (66–73) |
| E velocity, median (IQR) | 0.60 (0.51–0.71) |
| Septal e’ velocity, median (IQR) | 0.05 (0.04–0.07) |
| E/e’, median (IQR) | 10.7 (9.1–13.5) |
| FeNO, ppb, mean (SD) | 24.2 (15.6) |
aFeNO measurement was unsuccessful in 50 participants — these participants' data are included in all variables outside of FeNO. bUnless otherwise stated. BMI = body mass index. CABG = coronary artery bypass grafting. COPD = chronic obstructive pulmonary disease. FeNO = fractional exhaled nitric oxide. NYHA = New York Heart Association. PCI = percutaneous coronary intervention. ppb = parts per billion.