Characteristic | Total cohort, n (%)a,b |
---|---|
Participants | 277 (100) |
Age, years, median (IQR) | 73 (68–78) |
Sex | |
Male | 152 (54.9) |
Female | 125 (45.1) |
Ethnic group | |
White | 269 (97.1) |
Asian | 5 (1.8) |
Black | 2 (0.7) |
Mixed | 1 (0.4) |
Smoking status | |
Non-smoker | 133 (48.0) |
Ex-smoker | 136 (49.1) |
Current | 8 (2.9) |
BMI, kg/m2, median (IQR) | 27.6 (24.5–30.4) |
Asthma | 20 (7.2) |
COPD | 16 (5.8) |
Inhaled steroids | 12 (4.3) |
Atrial fibrillation | 39 (14.1) |
Diabetes | 38 (13.7) |
Hyperlipidaemia | 134 (48.4) |
Hypertension | 149 (53.8) |
Myocardial infarct | 12 (4.3) |
PCI | 11 (4.0) |
CABG | 5 (1.8) |
Chronic kidney disease | 35 (12.6) |
NYHA class | |
I | 178 (64.3) |
II | 89 (32.1) |
III | 10 (3.6) |
Socioeconomic class | |
1 (least deprived) | 67 (24.2) |
2 | 65 (23.5) |
3 | 85 (30.7) |
4 | 36 (13.0) |
5 (most deprived) | 21 (7.6) |
Missing | 3 (1.1) |
Ejection fraction, %, median (IQR) | 69 (66–73) |
E velocity, median (IQR) | 0.60 (0.51–0.71) |
Septal e’ velocity, median (IQR) | 0.05 (0.04–0.07) |
E/e’, median (IQR) | 10.7 (9.1–13.5) |
FeNO, ppb, mean (SD) | 24.2 (15.6) |
aFeNO measurement was unsuccessful in 50 participants — these participants' data are included in all variables outside of FeNO. bUnless otherwise stated. BMI = body mass index. CABG = coronary artery bypass grafting. COPD = chronic obstructive pulmonary disease. FeNO = fractional exhaled nitric oxide. NYHA = New York Heart Association. PCI = percutaneous coronary intervention. ppb = parts per billion.