Table 1. Baseline patient characteristics of individuals with AF stratified by DAT prescription
CharacteristicWhole sample (N = 8881), n %Not on DAT (n = 8465), n %On DAT (n = 416), n %
Sex
Male5024 (56.6)4738 (56.0)286 (68.8)
Female3857 (43.4)3727 (44.0)130 (31.3)
Age group, years
18–744581 (51.6)4364 (51.6)217 (52.2)
≥754300 (48.4)4101 (48.4)199 (47.8)
Ethnicity
White5628 (63.4)5406 (63.9)222 (53.4)
South Asian1069 (12.0)976 (11.5)93 (22.4)
Black1186 (13.4)1137 (13.4)49 (11.8)
Unknowna 998 (11.2)946 (11.2)52 (12.5)
IMD quintile
1 (least deprived)1782 (20.1)1716 (20.3)66 (15.9)
21784 (20.1)1705 (20.1)79 (19.0)
31765 (19.9)1675 (19.8)90 (21.6)
41774 (20.0)1682 (19.9)92 (22.1)
5 (most deprived)1774 (20.0)1686 (19.9)88 (21.2)
Unknown2 (0.02)1 (0.1)1 (0.2)
Clinical features
IHD, stroke, or TIA3177 (35.8)2837 (33.5)340 (81.7)
Diabetes or CKD4389 (49.4)4118 (48.6)271 (65.1)
Upper GI bleeding111 (1.2)105 (1.2)6 (1.4)
PPI/H2RA351 (84.4)
DAT prescribed >12 months274 (65.9)
Systolic blood pressure, mmHg
<1406682 (75.2)6356 (75.1)326 (78.4)
≥1401262 (14.2)1175 (13.9)87 (20.9)
Missing337 (3.8)334 (3.9)3 (0.7)
Smoking status
Never smoked3944 (44.4)3765 (44.5)179 (43.0)
Ex-smoker2742 (30.9)2602 (30.7)140 (33.7)
Current smoker792 (8.9)737 (8.7)55 (13.2)
Unknown1403 (15.8)1361 (16.1)42 (10.1)
BMI, kg/m2
<20725 (8.2)693 (8.2)32 (7.7)
20–293733 (42.0)3559 (42.0)174 (41.8)
≥303002 (33.8)2832 (33.5)170 (40.9)
Unknown1421 (16.0)1381 (16.3)40 (9.6)
Median (IQR)28.4 (24.6–32.9)28.3 (24.6–32.9)29.3 (25.5–33.4)
  • aEthnicity not stated or missing. AF = atrial fibrillation. BMI = body mass index. CKD = chronic kidney disease. DAT = dual antithrombotic therapy. GI = gastrointestinal. H2RA = H2-receptor antagonist. IHD = ischaemic heart disease. IMD = Index of Multiple Deprivation. IQR = interquartile range. PPI = proton pump inhibitor. TIA = transient ischaemic attack.