Table 4. Full sample regression coefficients

Category	Preferred model	Model 2	Model 3	Model 4	Model 5
Time	0.002^a	0.002^a	0.002^a	0.001^a	0.004
Intervention	–0.038^a	–0.036^a	–0.033^a	0.033^a	0.263^a
Post	–0.002^a	–0.002^a	–0.002^a	–0.000	–0.003
Seasonal adjustment	YES	YES	YES	NO	NO
Age bands	YES	YES	NO	NO	NO
Sex	YES	YES	NO	NO	NO
Diagnoses	YES	NO	NO	NO	NO
Practice random effects	YES	YES	YES	YES	NO

^a P<0.001.