ADE type | High-risk prescribing |
---|---|
Gastrointestinal | NSAID or aspirin without gastroprotection in patient with prior peptic ulcera or |
NSAID without gastroprotection in patient aged ≥75 years or | |
NSAID without gastroprotection in patient aged ≥65 years taking aspirin or | |
Clopidogrel without gastroprotection in patient aged ≥65 years taking aspirin or | |
NSAID without gastroprotection in patient taking an oral anticoagulant or | |
Aspirin or clopidogrel without gastroprotection in patient taking an oral anticoagulant | |
Renal | NSAID in patient taking both renin-angiotensin system blocker and diuretic or |
NSAID in patient with chronic kidney disease (eGFR <60 at the most recent test) | |
Cardiac | NSAID in patient with history of heart failurea |
Combined | Any of the above criteria |
Prescribed medication is defined as any prescription for this category of medication in the previous 14 weeks, as identified from the electronic prescribing database of the participating practices. This time period is used because in New Zealand most medication is prescribed for a maximum of 12 weeks.
aObtained general practice electronic disease coding from the participating practices.
ADE = adverse drug event. eGFR = estimated glomerular filtration rate. NSAID = non-steroidal anti-inflammatory drug.