Table 3. Multilevel logistic regression analysis of excessive polypharmacy in care home residents
CharacteristicCategoryDispensed ≥10 drugs,n = 1444, n (%)OR univariable(95% CI)b,cOR multivariable(95% CI)c,d
Age group, years60–6419 (21.8)RefRef
65–6953 (34.4)1.76 (0.94 to 3.29)1.80 (0.96 to 3.38)
70–74101 (35.4)1.79 (1.00 to 3.21)1.86 (1.04 to 3.34)
75–79163 (34.0)1.67 (0.96 to 2.94)1.73 (0.98 to 3.03)
80–84302 (34.2)1.65 (0.96 to 2.85)1.75 (1.01 to 3.02)
85–89393 (33.9)1.60 (0.93 to 2.75)1.66 (0.97 to 2.87)
90–94288 (28.9)1.18 (0.68 to 2.04)1.19 (0.69 to 2.07)
≥95125 (29.4)1.14 (0.64 to 2.01)1.08 (0.61 to 1.92)
SexMale422 (33.2)Ref
Female1022 (32.0)0.89 (0.77 to 1.03)
Dementia statusNo dementia802 (34.7)RefRef
Dementia642 (29.7)0.78 (0.68 to 0.89)0.73 (0.64 to 0.84)
Care home typeNursing743 (28.6)RefRef
Residential701 (37.5)1.49 (1.19 to 1.85)1.50 (1.19 to 1.88)
RAD scoreLow1045 (34.4)RefRef
Medium175 (29.4)0.75 (0.54 to 1.06)0.72 (0.52 to 0.99)
High224 (26.9)0.69 (0.51 to 0.93)0.77 (0.56 to 1.04)
NHS health boardTayside805 (30.1)RefRef
Fife639 (35.7)1.24 (0.99 to 1.57)1.37 (1.09 to 1.71)
Intraclass correlation coefficient, % (95% CI)8.9 (5.9 to 11.6)Null model7.1 (4.2 to 9.5)Adjusted model
  • aWithin category %. bNumber of groups = 147; residents in all models = 4468. Service sector and care home size not fitted in models as collinear with care home status. cUnless otherwise stated. dC-statistic = 0.685. – = variable not fitted. RAD = Risk Assessment Document.