Mannheim44 | Sydney45 | Hawaii43 | Antwerp46 | AgeCoDe47 | France20 | This study | |
---|---|---|---|---|---|---|---|
Participant selection | |||||||
Series | C | C | C | C | R | C | C |
Symptomatic | No | Noa | No | No | No | Yesa | Yes |
Characteristics of participants | |||||||
Number (index test) | 3721 | 433 | 303 | 1003 | 3242 | 1453 | 240 |
Mean age (years) | 76 | 85 | 75 | 75 | 80 | 81 | 80 |
% Female | 70 | 84 | 63 | 63 | 66 | 71 | 47 |
% with dementia | 29 | 25 | 9 | 2 | 2 | 50 | 55 |
Target condition and verification with reference standard | |||||||
Verified n | 407 | 105 | 303 | 101 | 22 | 385 | 240 |
Verified % | 11 | 24 | 100 | 1 | 70 | 26 | 100 |
GP judgment (%) | |||||||
Not impaired | 36 | 76 | 33 | – | 94 | 48 | 14 |
Cognitive impairment | 41 | – | – | – | – | – | 40 |
Dementia | 23 | 19 | 33 | – | 6 | 26 | 36 |
Uncertain | – | 5 | 33 | – | – | 22 | – |
Diagnostic accuracy of clinical judgment for dementia | |||||||
Sensitivity | 91 | 42 | – | 100 | 51 | 73 | 56 |
Specificity | 76 | 89 | – | 100 | 96 | 58 | 89 |
C = consecutive. R = random; symptomatic: symptoms required for participation. % verified = number underwent reference test or number underwent index test. % with dementia = number with dementia or number verified.
↵a Participants were not presenting with symptoms but GPs were asked to maximise the inclusion of people with suspected dementia that was not reported.