Table 1. Programme and trial phases and timelines

Stage and key aims	Duration	Key dates
Develop f easibility stageAims:To develop and refine the intervention modelTo agree outcome measuresTo test recruitment processes	24 months	2014–2016
Randomised controlled trial : internal pilotAims:To further test feasibility of both recruitment and the intervention delivery for patients and GP practices.To assess recruitment against objectives: GP practice recruitment rates – 8 GP practices per site (24 total) Participant eligibility rates – 24 participants per site (72 total) To assess delivery and safety of intervention—for example, intervention delivery (care partners in place) and adverse events such as crisis care (home treatment teams), and admissions (psychiatric).To review initial sample size target of 336 participants	6 months	Trial started: 1/10/2017Trial registered: 16/10/2017First participant recruited: 8/6/2018
R CT (completion of RCT following internal pilot):Aim:To establish the clinical and cost-effectiveness of primary care based collaborative care for people with a clinical diagnosis of schizophrenia, bipolar, or other types of psychosis^a	Completion of recruitmentFollow up: 10–12 months	Recruitment end date: 28/2/2020Follow up end: 28/12/2020Data collection end date:31/3/2020Study end date: 30/04/2021

Stage and key aims

Duration

Key dates

Develop f easibility stageAims:To develop and refine the intervention modelTo agree outcome measuresTo test recruitment processes

24 months

2014–2016

Randomised controlled trial : internal pilotAims:To further test feasibility of both recruitment and the intervention delivery for patients and GP practices.To assess recruitment against objectives:

GP practice recruitment rates – 8 GP practices per site (24 total)
Participant eligibility rates – 24 participants per site (72 total)

To assess delivery and safety of intervention—for example, intervention delivery (care partners in place) and adverse events such as crisis care (home treatment teams), and admissions (psychiatric).To review initial sample size target of 336 participants

6 months

Trial started: 1/10/2017Trial registered: 16/10/2017First participant recruited: 8/6/2018

R CT (completion of RCT following internal pilot):Aim:To establish the clinical and cost-effectiveness of primary care based collaborative care for people with a clinical diagnosis of schizophrenia, bipolar, or other types of psychosis^a

Completion of recruitmentFollow up: 10–12 months

Recruitment end date: 28/2/2020Follow up end: 28/12/2020Data collection end date:31/3/2020Study end date: 30/04/2021

a Revised recruitment target of 204 participants with a diagnosis of schizophrenia, bipolar, or other types of psychosis from ~34 clusters (GP practices), based on prespecified sample size recalculation (December 2019) and funder requirements (January 2020).
RCT
Randomised controlled trial