Valid n | All included children(n = 175) | Valid n | Eligible, but included in parallel cohort study(n = 70) | Valid n | GP prescribed ondansetron(n = 19) | ||
---|---|---|---|---|---|---|---|
Demographics | |||||||
Media age, years (IQR) | 175 | 1.50 (0.9–2.1) | 69 | 1.5 (1.0–2.1) | 18 | 2.0 (1.0–3.0) | |
Females, n (%) | 175 | 88 (50.3%) | 70 | 36 (51.4%) | 19 | 10 (52.6%) | |
Symptoms | |||||||
Median weight, kg (IQR) | 169 | 11.0 (9.5–14.0) | 61 | 11.0 (9.1–13.5) | 16 | 12.7 (11.0–16.5) | |
Median vomiting duration, days (IQR) | 174 | 2.0 (1.0–3.0) | 70 | 2.0 (1.0–3.0) | 19 | 3.0 (2.0–4.0) | |
Median vomiting frequency per 24 hours (IQR) | 171 | 5.0 (4.0–10.0) | 66 | 7.0 (4.0–10.0) | 19 | 8.0 (6.0–10.0) | |
Diarrhoea present, n (%) | 174 | 124 (71.3%) | 70 | 49 (70.0%) | 19 | 13 (68.4%) | |
Median diarrhoea duration, daysa (IQR) | 124 | 2.0 (1.0–3.0) | 49 | 1.0 (0.0–3.3) | 13 | 3.0 (1.0–4.0) | |
Median diarrhoea frequency per 24 hoursa (IQR) | 123 | 3.0 (2.00–5.0) | 44 | 1.0 (0.0–4.0) | 13 | 1.0 (0.0–4.0) | |
Management | |||||||
Median GP-assessed degree of dehydration (0–100), (IQR) | 170 | 20.0 (10.0–40.0) | 64 | 25.0 (10.0–39.0) | 16 | 38.0 (30.0–58.0) | |
Use of concomitant medication | 175 | 65 (37.1%) | 66 | 19 (28.8%) | 19 | 10 (52.6%) | |
Risk factors and alarm symptoms | |||||||
Dehydration: risk factorsb | 1 | 175 | 63 (36.0%) | 70 | 22 (31.4%) | 19 | 7 (36.8%) |
≥2 | 175 | 18 (10.3%) | 70 | 2 (2.9%) | 19 | 0 (0.0%) | |
Dehydration: alarm symptomsc | 1 | 175 | 32 (18.3%) | 70 | 5 (7.1%) | 19 | 0 (0.0%) |
≥2 | 175 | 2 (1.1%) | 70 | 3 (4.3%) | 19 | 0 (0.0%) |
Bold results indicate a significant difference. aNumbers only presented for those participants with diarrhoea.bRisk factors assessed at baseline were as follows: ≥6 watery stools or diarrhoea, fever (>38°C), and reduced intake in the last 12 hours.cAlarm symptoms assessed at baseline were as follows: confused or decreased consciousness, bradycardia, weak peripheral heartbeat pulsations, capillary refill >4 seconds, skin pitch >4 seconds, cold or marbled extremities, and reduced urine output in the last 24 hours.