| 1: Classic erythema migrans (EM) rash (n = 7) | Lyme diseaseBite(10 differentials in total) | 52 | RashLyme diseaseEMSuspected Lyme disease(5 Read codes in total) | 3311 | 5 | 5 | 5 |
| Lyme disease(3 differentials in total) | 6 |
| 2: Borrelial lymphocytoma (n = 7) | No differential was mentioned more than once.(13 differentials in total) | Ear swelling(5 Read codes in total, one GP wouldn’t code the case) | 2 | 2 | 3 | 4 |
| 3: Acrodermatitis chronica atrophicans (n = 8) | Alcohol-related issueVitamin B12 deficiency(19 differentials in total) | 43 | Peripheral neuropathySensory loss(4 Read codes in total, one GP wouldn’t code the case) | 32 | 8 | 2 | 4 |
| 4: Bell’s palsy (n = 7) | Bell’s palsyBrain tumourSpace occupying lesion(9 differentials in total) | 732 | Bell’s palsyNerve palsy(5 Read codes in total) | 42 | 5 | 1 | 6 |
| Bell’s palsyBrain tumourLyme disease(7 differentials in total) | 721 |
| 5: Recurrent synovitis of knees (n = 7) | OsteoarthritisRheumatoid arthritisGout(9 differentials in total) | 543 | Knee painSynovitis(4 Read codes in total) | 32 | 7 | 7 | 7 |
| 6: Multiple EM rashes (n = 7) | Insect biteFungal infectionLyme disease(11 differentials in total) | 633 | Non-specific rashErythema migrans(6 Read codes in total, one GP wouldn’t code the case) | 21 | 3 | 6 | 0 |
| 7: Heart rhythm abnormalities (n = 7) | ArrhythmiaPalpitations(11 differentials in total) | 43 | Palpitations(2 Read codes in total, one GP wouldn’t code the case) | 5 | 6 | 2 | 2 |
| 8: Fatigue, post-exertional malaise, anxiety, headaches, and memory issues (n = 5) | Thyroid problemsChronic fatigue syndromeDepression(8 differentials in total) | 433 | Tired all the time(3 Read codes in total, one GP wouldn’t code the case) | 3 | 5 | 1 | 3 |
| Thyroid problemsChronic fatigue syndromeDepressionLyme disease(7 differentials in total) | 3221 |
| 9: Fatigue, arthralgia, poor ability to concentrate, myalgia, mood swings (n = 7) | DepressionAnaemiaThyroid problems(13 differentials in total) | 533 | FatiguePolyarthralgia(4 Read codes in total, one GP wouldn’t code the case) | 32 | 7 | 5 | 1 |
| 10: Non-engorged tick attached to scalp (n = 6) | Cutaneous hornForeign bodySkin lesionTick(10 differentials in total) | 2222 | Skin lesionTick bite(4 Read codes in total) | 22 | 4 | 1 | 0 |
| 11: Poor fine motor movements, rash 2 months previously at scout camp. This had been treated with erythromycin (n = 8) | DepressionNeurological conditionLyme disease(18 differentials in total) | 441 | Feeling lowLow moodNeurological symptoms(4 codes in total, one GP wouldn’t code the case) | 222 | 7 | 0 | 3 |