Table 2. Risk of bias assessment for the included in vivo study
BiasRapid review authors’ judgmentReason for judgment
Random sequence generationHigh riskNon-randomised trial
Allocation concealmentHigh riskOpen-label
BlindingHigh riskOpen-label
Incomplete outcome dataHigh riskIntention-to-treat analysis not performed
Selective reportingUnclear riskNo adverse event data reported, although the authors state that this will be reported separately at the end of the trial
Other biasHigh riskUnder-powered according to the authors’ own power calculation