Table 2. Summary of diagnostic performance of NEWS to predict adverse outcome
5 day outcome30 day outcome
NEWS ≥5NEWS ≥7NEWS ≥5NEWS ≥7
Death (95% CI)Death or critical care admission (95% CI)Death (95% CI)Death or critical care admission (95% CI)Death (95% CI)Death or critical care admission (95% CI)Death (95% CI)Death or critical care admission (95% CI)
NEWS recorded by GP
Sensitivity49%(33-65)38%(31-47)21%(10-36)25%(18-33)37%(29-46)37%(30-45)23%(16-31)24%(18-32)
Specificity83%(81-84)84%(82-85)93%(91-94)94%(92-95)83%(82-85)84%(82-85)93%(92-94)94%(92-95)
Positive predictive value5%(3-8)15%(12-19)5%(2-10)22%(16-29)12%(9-16)15%(12-19)17%(12-24)23%(17-30)
Negative predictive value99%(98-99)95%(94-96)98%(98-99)94%(93-95)96%(95-96)94%(93-95)95%(94-96)94%(93-95)
Positive likelihood ratio2.8(2.1–3.9)2.3(1.9–2.9)2.8(1.5–5.1)3.9(2.8–5.3)2.2(1.8–2.8)2.3(1.8–2.8)3.4(2.4–4.8)3.8(2.8–5.2)
Negative likelihood ratio0.6(0.5–0.8)0.7(0.7–0.8)0.9(0.7–1.0)0.8(0.7–0.9)0.8(0.7–0.9)0.8(0.7–0.9)0.8(0.8–0.9)0.8(0.7–0.9)
NEWS recorded by ambulance
Sensitivity62%(46-77)53%(45-62)42%(27-59)32%(24-40)54%(45-62)53%(45-61)24%(18-30)31%(24-39)
Specificity67%(64-70)69%(66-72)85%(83-87)86%(84-88)69%(66-72)69%(66-72)86%(84-88)86%(84-88)
Positive predictive value7%(4-10)21%(17-25)9%(6-15)26%(20-33)19%(15-23)21%(17-26)24%(18-30)26%(20-33)
Negative predictive value98%(97-99)91%(88-93)98%(96-98)89%(87%–91%)92%(90-94)90%(88-92)86%(84-88)89%(87-91)
Positive likelihood ratio1.9(1.5–2.5)1.7(1.4–2.1)2.8(1.9–4.1)2.3(1.7–3.1)1.7(1.4–2.1)1.7(1.5–2.1)1.7(1.3–2.3)2.2(1.7–3.0)
Negative likelihood ratio0.6(0.4–0.8)0.7(0.6–0.8)0.7(0.5–0.9)0.8(0.7–0.9)0.7(0.6–0.8)0.7(0.6–0.8)0.9(0.8–1.0)0.8(0.7-.0.9)
  • NEWS = national early warning scores.