| Chronic or intermittent diarrhoea | Addison's disease |
| Failure to thrive or faltering growth (in children) | Amenorrhoea |
| Persistent and unexplained gastrointestinal symptoms, including nausea or vomiting | Aphthous stomatitis (mouth ulcers) |
| Prolonged fatigue | Autoimmune liver conditions |
| Recurrent abdominal pain, cramping, or distension | Autoimmune myocarditis |
| Sudden or unexpected weight loss | Chronic thrombocytopenia purpura |
| Unexplained iron deficiency anaemia or other unspecified anaemia | Dental enamel defects |
| Autoimmune thyroid disease | Depression or bipolar disorder |
| Dermatitis herpetiformis | Down syndrome |
| Irritable bowel syndrome | Epilepsy |
| Type 1 diabetes | Low trauma fracture |
| First-degree relatives with coeliac disease | Lymphoma |
| Metabolic bone disease (such as rickets or osteomalacia) |
| Microscopic colitis |
| Persistent or unexplained constipation |
| Persistently raised liver enzymes with unknown cause |
| Polyneuropathy |
| Recurrent miscarriage |
| Reduced bone mineral density |
| Sarcoidosis |
| Sjögren's syndrome |
| Turner's syndrome |
| Unexplained alopecia |
| Unexplained subfertility |