| Mean outcome (95% CI)a | Crude intervention- control difference (95% CI); P valueb | Adjusted intervention- control difference (95% CI); P valueb | |||
|---|---|---|---|---|---|
| Intervention (clusters = 15) | Control (clusters = 15) | ||||
| Primary outcomes | |||||
| BODE index score changec | -1.67 (-2.18 to -1.16) | -0.66 (-1.09 to -0.22) | -1.01 (-1.65 to -0.37); 0.003 | -0.96 (-1.49 to -0.44); 0.001 | |
| COPD controld | 66.88% (54.99 to 78.77) | 38.20% (22.35 to 54.06) | 28.68% (9.68 to 47.67); 0.005 | 29.03% (12.41 to 45.64); 0.001 | |
| Secondary outcome | |||||
| Quit rate among smokerse | 53.90% (34.98 to 72.82) | 17.52% (7.36 to 27.69) | 36.38% (15.66 to 57.10); 0.002 | 31.98% (15.42 to 48.54); 0.001 | |
| Follow-up adherencef | 65.54% (52.64 to 78.44) | 25.17% (14.86 to 35.47) | 40.38% (24.57 to 56.18); <0.001 | 40.40% (24.15 to 56.67); <0.001 | |
aArm-specific mean outcomes and their 95% confidence intervals are calculated from cluster-level mean and/or proportion summary values of outcomes. bAll intervention minus control differences (that is, intervention effect estimates) are based on crude and/or covariate-adjusted analysis of cluster-level mean and/or proportion summary values of outcomes. cBODE index score change calculated as outcome at 6-month follow-up minus outcome at baseline. dCOPD control defined as BODE index ≤ 2 at 6-month follow-up. eQuit rate among smokers calculated as smokers who had quit smoking at 6-month follow-up. fFollow-up adherence defined as attending ≥4 follow-up visits. All analyses use only complete cases.
BODE = Body mass index, airway Obstruction, Dyspnoea, Exercise capacity. CI = confidence intervals. COPD = chronic obstructive pulmonary disease.