Table 3 Univariable and multivariable associations of overall CAM use

		Univariable analysis		Multivariable analysis
Factor	Category	Odds ratio (95% CI)	P value	Odds ratio (95% CI)	P value
Sex	Male	1		1
	Female	1.74 (1.48 to 2.04)	<0.001	1.79 (1.50 to 2.13)	<0.001
Age	15–24	1		1
	25–34	1.75 (1.28 to 2.4)	<0.001	1.81 (1.24 to 2.65)	0.002
	35–44	2.74 (2.02 to 3.71)	<0.001	2.50 (1.70 to 3.69)	<0.001
	45–54	2.47 (1.83 to 3.34)	<0.001	2.04 (1.37 to 3.03)	<0.001
	55–64	2.29 (1.67 to 3.14)	<0.001	2.09 (1.38 to 3.15)	<0.001
	65+	1.48 (1.09 to 2.02)	0.012	1.49 (0.95 to 2.34)	0.081
Ethnicity	White	1		1
	Mixed	1.49 (0.75 to 2.98)	0.26	1.73 (0.93 to 3.24)	0.085
	Asian	0.35 (0.24 to 0.51)	<0.001	0.46 (0.33 to 0.66)	<0.001
	Black	0.44 (0.23 to 0.82)	0.01	0.56 (0.31 to 0.99)	0.047
	Other	0.95 (0.46 to 1.98)	0.89	0.78 (0.36 to 1.68)	0.52
Housing tenure	Owner			1
	Rented	0.61 (0.51 to 0.72)	<0.001	0.84 (0.68 to 1.04)	0.11
Income	Low (up to £11 499)	1		Not conducted, due to 30% missing data
	Medium (£11 500–£24 999)	1.13 (0.83 to 1.52)	0.43
	High (£25 000 or more)	1.78 (1.38 to 2.31)	<0.001
Marital status	Married	1		1
	Single	0.72 (0.6 to 0.86)	<0.001	1.21 (0.96 to 1.52)	0.11
	Widowed/divorced/separated	0.83 (0.65 to 1.05)	0.12	1.04 (0.79 to 1.38)	0.77
Region	North	1
	Midlands	1.07 (0.85 to 1.35)	0.55	1.09 (0.86 to 1.37)	0.47
	South	1.69 (1.4 to 2.06)	<0.001	1.46 (1.18 to 1.81)	<0.001
	London	0.83 (0.63 to 1.1)	0.19	0.90 (0.68 to 1.20)	0.49
Working status	Employed	1		1
	Student	0.48 (0.34 to 0.68)	<0.001	0.89 (0.59 to 1.35)	0.60
	Unemployed	0.65 (0.55 to 0.77)	<0.001	0.74 (0.59 to 0.92)	0.008
Social grade	(per grade)	0.77 (0.73 to 0.82)	<0.001	0.82 (0.76 to 0.88)	<0.001