Table 2. Univariable analysis of diagnoses depending on stage with odds ratio >1.5a in patients in primary care during 12 months before lung cancer diagnosis
Stage I–III (M0b)Stage IV (M1b)
ICD-10 code
and diagnosis
Prevalence % OR (95% CI)c ICD-10 code
and diagnosis
Prevalence % OR (95% CI)c
D51 Vitamin B12 deficiency anaemia3.86.7 (1.6 to 27.9)L20 Atopic dermatitis1.212.0 (1.2 to 115.4)
R060 Dyspnoea8.45.0 (2.0 to 12.7)R042 Haemoptysis2.19.6 (1.9 to 49.7)
J42 Unspecified chronic bronchitis3.85.0 (1.3 to 18.6)I26 Pulmonary embolism1.78.0 (1.5 to 43.7)
J44 COPD20.64.3
(2.4 to 7.5)
W00 Fall due to ice and snow1.78.0 (1.5 to 43.7)
I73 Other peripheral vascular diseases4.64.2 (1.3 to 13.9)M05 Rheumatoid arthritis with rheumatoid factor2.94.7 (1.6 to 13.9)
B34 Viral infection of unspecified site5.44.0 (1.4 to 11.4)N20 Calculus of kidney and ureter2.14.5 (1.2 to 17.1)
R05 Cough13.83.8
(2.0 to 7.5)
W19 Unspecified fall2.54.3 (1.3 to 14.3)
J18 Pneumonia12.23.2
(1.6 to 6.2)
J18 Pneumonia 9.53.8
(2.1 to 7.0)
R52 Pain, unspecified10.72.3
(1.1 to 4.7)
G40 Epilepsy and current seizures2.53.7 (1.2 to 11.6)
N30 Cystitis14.52.0
(1.1 to 3.6)
R05 Cough14.93.6
(2.2 to 5.8)
J20 Acute bronchitis16.01.8
(1.1 to to 3.2)
I73 Other peripheral vascular diseases7.03.6
(1.8 to 6.8)
M54 Back pain18.31.8
(1.1 to 3.1)
R22 Localised swelling, mass, and lump of skin and subcutaneous tissue3.73.1
(1.3 to 7.5)
M06 Other rheumatoid arthritis2.53.0
(1.0 to 8.6)
J44 COPD15.33.0
(1.9 to 4.7)
R060 Dyspnoea5.82.5
(1.3 to 4.9)
K51 Diverticular disease of intestine3.72.4
(1.0 to 5.4)
J20 Acute bronchitis14.92.3
(1.5 to 3.5)
R52 Pain, unspecified11.22.0
(1.3 to 3.3)
M54 Back pain 19.82.0
(1.3 to 2.8)
  • aOdds ratio are calculated between cases and controls. Diagnostic codes with OR <1.5 are omitted. bTNM Classification of Malignant Tumours code. cP<0.05. COPD = chronic obstructive pulmonary disease.