RT Journal Article SR Electronic T1 Predictors of treatment outcomes for patients with persistent physical symptoms in primary care: findings from a cluster randomised controlled trial JF BJGP Open JO BJGP Open FD Royal College of General Practitioners SP BJGPO.2024.0004 DO 10.3399/BJGPO.2024.0004 A1 Abrahamsen, Cathrine A1 Wangen, Knut Reidar A1 Lindbaek, Morten A1 Werner, Erik Lønnmark YR 2024 UL http://bjgpopen.org/content/early/2024/12/09/BJGPO.2024.0004.abstract AB Background Persistent physical symptoms (PPS) are consistently prevalent among primary care patients. PPS can negatively affect quality of life, healthcare costs, and work participation. In a previous study, we found substantially improved outcomes and reduced sick leave for patients treated by a work-focused communication tool, known as the Individual Challenge Inventory Tool (ICIT), compared with a control group.Aim To examine predictors of treatment outcome in patients who received treatment by ICIT, delivered by the patient’s GP.Design & setting This study is based on the findings of our previous cluster randomised controlled trial undertaken in Norway.Method Regression analyses of the intervention group were used to identify predictors (all measured at baseline) of improvements in Patient Global Impression of Change (PGIC) and sick leave after 11 weeks follow-up.Results Living alone predicted improvement in the adjusted model (odds ratio [OR] 4.03, 95% confidence interval [CI] = 1.33 to 12.25, P = 0.014). Receiving long-term benefits predicted improved PGIC in both the unadjusted (OR 2.30, 95% CI = 1.21 to 4.39, P = 0.011) and adjusted models (OR 2.46, 95% CI = 1.04 to 5.83, P = 0.040). In addition, living alone predicted reduced sick leave in the adjusted model (OR 3.23, 95%CI = 1.11 to 9.42, P = 0.032).Conclusion In general, there were few factors to predict the outcome of the work-focused communication tool. We therefore suggest that this work-focused communication tool is applicable to most patients with PPS. GPs may consider using the ICIT for all primary care patients who exhibit ineffective coping strategies in their daily lives and work, especially those who live alone.