PT  - JOURNAL ARTICLE
AU  - Sisk, Rose
AU  - Cameron, Rory
AU  - Tahir, Waqas
AU  - Sammut-Powell, Camilla
TI  - Diagnosis codes underestimate chronic kidney disease incidence compared with eGFR-based evidence: a retrospective observational study of patients with type 2 diabetes in UK primary care
AID  - 10.3399/BJGPO.2023.0079
DP  - 2024 Apr 01
TA  - BJGP Open
PG  - BJGPO.2023.0079
VI  - 8
IP  - 1
4099  - http://bjgpopen.org/content/8/1/BJGPO.2023.0079.short
4100  - http://bjgpopen.org/content/8/1/BJGPO.2023.0079.full
SO  - BJGP Open2024 Apr 01; 8
AB  - Background Type two diabetes (T2D) is a leading cause of both chronic kidney disease (CKD) and onward progression to end-stage renal disease. Timely diagnosis coding of CKD in patients with T2D could lead to improvements in quality of care and patient outcomes.Aim To assess the consistency between estimated glomerular filtration rate (eGFR)-based evidence of CKD and CKD diagnosis coding in UK primary care.Design & setting A retrospective analysis of electronic health record data in a cohort of people with T2D from 60 primary care centres within England between 2012 and 2022.Method We estimated the incidence rate of CKD per 100 person–years using eGFR-based CKD and diagnosis codes. Logistic regression was applied to establish which attributes were associated with diagnosis coding. Time from eGFR-based CKD to entry of a diagnosis code was summarised using the median and interquartile range.Results The overall incidence of CKD was 2.32 (95% confidence interval [CI] = 2.24 to 2.41) and significantly higher for eGFR-based criteria than diagnosis codes: 1.98 (95% CI = 1.90 to 2.05) versus 1.06 (95% CI = 1.00 to 1.11), respectively; P<0.001. Only 45.4% of CKD incidences identified using eGFR-based criteria had a corresponding diagnosis code. Patients who were younger, had a higher CKD stage (G4), had an observed urine albumin-to-creatinine ratio (A1), or no observed HbA1c in the past year were more likely to have a diagnosis code.Conclusion Diagnosis coding of patients with eGFR-based evidence of CKD in UK primary care is poor within patients with T2D, despite CKD being a well-known complication of diabetes.