RT Journal Article SR Electronic T1 Symptom patterns and life with post-acute COVID-19 in children aged 8–17 years: a mixed-methods study protocol JF BJGP Open JO BJGP Open FD Royal College of General Practitioners SP BJGPO.2022.0149 DO 10.3399/BJGPO.2022.0149 VO 7 IS 2 A1 Faux-Nightingale, Alice A1 Burton, Claire A1 Twohig, Helen A1 Blagojevic-Bucknall, Milica A1 Carroll, Will A1 Chew-Graham, Carolyn A A1 Dunn, Kate A1 Gilchrist, Francis A1 Helliwell, Toby A1 Lawton, Oliver A1 Lawton, Sarah A1 Mallen, Christian A1 Saunders, Benjamin A1 van der Windt, Danielle A1 Welsh, Victoria YR 2023 UL http://bjgpopen.org/content/7/2/BJGPO.2022.0149.abstract AB Background While there is a substantial body of knowledge about acute COVID-19, less is known about long-COVID, where symptoms continue beyond 4 weeks.Aim To describe longer-term effects of COVID-19 infection in children and young people (CYP) and identify their needs in relation to long-COVID.Design & setting This study comprises an observational prospective cohort study and a linked qualitative study, identifying participants aged 8–17 years in the West Midlands of England.Method CYP will be invited to complete online questionnaires to monitor incidences and symptoms of COVID-19 over a 12-month period. CYP who have experienced long-term effects of COVID will be invited to interview, and those currently experiencing symptoms will be asked to document their experiences in a diary. Professionals who work with CYP will be invited to explore the impact of long-COVID on the wider experiences of CYP, in a focus group. Descriptive statistics will be used to describe the incidence and rates of resolution of symptoms, and comparisons will be made between exposed and non-exposed groups. Logistic regression models will be used to estimate associations between candidate predictors and the development of long-COVID, and linear regression will be used to estimate associations between candidate predictors. Qualitative data will be analysed thematically using the constant comparison method.Conclusion This study will describe features and symptoms of long-COVID and explore the impact of long-COVID within the lives of CYP and their families, to provide better understanding of long-COVID and inform clinical practice.