RT Journal Article SR Electronic T1 Exploring the impact of prior spontaneous miscarriage on stress among pregnant women during the first trimester: an observational study JF BJGP Open JO BJGP Open FD Royal College of General Practitioners SP BJGPO.2022.0100 DO 10.3399/BJGPO.2022.0100 A1 Coralie Barbe A1 Justine Ouy A1 Marie Boiteux-Chabrier A1 Leïla Bouazzi A1 Bach-Nga Pham A1 Sandra Carrau-Truillet A1 Aline Hurtaud YR 2023 UL http://bjgpopen.org/content/early/2023/01/23/BJGPO.2022.0100.abstract AB Background Spontaneous miscarriage (SM) is the most common complication of pregnancy. Its psychological repercussions are widely documented but few studies have investigated its effect on women’s experience of a subsequent pregnancy.Aim To evaluate the impact of prior SM on the level of stress experienced by pregnant women during the first trimester of pregnancy.Design and setting Cross-sectional, observational study, which was conducted between June and October 2021 in France.Method A self-report questionnaire was distributed to women in the first trimester of pregnancy. Stress was assessed using the Antenatal Perceived Stress Inventory to yield an overall score and a score for three dimensions ('medical and obstetric risks or fetal health'; 'psychosocial changes during pregnancy'; and the ‘prospect of childbirth'). Women with a history of prior SM and those without were compared.Results In total, 93 women were included; 63 without and 30 with a history of prior SM. Prior SM was not associated with the overall score. The score for the dimension 'medical and obstetric risks or fetal health' was significantly higher in women with prior SM (3.00±0.86 versus 2.34±0.80; β = 0.61 [95% confidence interval {CI} = 0.25 to 0.96]; P = 0.001). Prior SM was significantly associated with the items 'the baby’s health' (P = 0.048) and 'the echography' (P = 0.002).Conclusion This study shows a significant impact of prior SM on the level of stress of pregnant women during the first trimester, particularly relating to the medical and obstetric risks or fetal health, underlining the need for appropriate psychological support to be provided to women who experience SM.