RT Journal Article SR Electronic T1 Point-of-care testing, antibiotic prescribing, and prescribing confidence for respiratory tract infections in primary care: a prospective audit in 18 European countries JF BJGP Open JO BJGP Open FD Royal College of General Practitioners SP BJGPO.2021.0212 DO 10.3399/BJGPO.2021.0212 VO 6 IS 2 A1 van der Velden, Alike W A1 van de Pol, Alma C A1 Bongard, Emily A1 Cianci, Daniela A1 Aabenhus, Rune A1 Balan, Anca A1 Böhmer, Femke A1 Bralić Lang, Valerija A1 Bruno, Pascale A1 Chlabicz, Slawomir A1 Coenen, Samuel A1 Colliers, Annelies A1 García-Sangenís, Ana A1 Ghazaryan, Hrachuhi A1 Godycki-Ćwirko, Maciej A1 Jensen, Siri A1 Lionis, Christos A1 van der Linde, Sanne R A1 Malania, Lile A1 Pauer, Jozsef A1 Tomacinschii, Angela A1 Vellinga, Akke A1 Zastavnyy, Ihor A1 Emmerich, Susanne A1 Zerda, Adam A1 Verheij, Theo J A1 Goossens, Herman A1 Butler, Christopher C YR 2022 UL http://bjgpopen.org/content/6/2/BJGPO.2021.0212.abstract AB Background Between-country differences have been described in antibiotic prescribing for respiratory tract infection (RTI) in primary care, but not yet for diagnostic testing procedures and prescribing confidence.Aim To describe between-country differences in RTI management, particularly diagnostic testing and antibiotic prescribing, and investigate which factors relate to antibiotic prescribing and GPs’ prescribing confidence.Design & setting Prospective audit in 18 European countries.Method An audit of GP-registered patient, clinical, and management characteristics for patients presenting with sore throat and/or lower RTI (n = 4982), and GPs' confidence in their antibiotic prescribing decision. Factors related to antibiotic prescribing and confidence were analysed using multi-level logistic regression.Results Antibiotic prescribing proportions varied considerably: <20% in four countries, and >40% in six countries. There was also considerable variation in point-of-care (POC) testing (0% in Croatia, Moldova, and Romania, and >65% in Denmark and Norway, mainly for C-reactive protein [CRP] and group A streptococcal [strep A] infection), and in laboratory or hospital-based testing (<3% in Hungary, the Netherlands, and Spain, and >30% in Croatia, Georgia, Greece, and Moldova, mainly chest X-ray and white blood cell counting). Antibiotic prescribing was related to illness severity, comorbidity, age, fever, and country, but not to having performed a POC test. In nearly 90% of consultations, GPs were confident in their antibiotic prescribing decision.Conclusion Despite high confidence in decisions about antibiotic prescribing, there is considerable variation in the primary care of RTI in European countries, with GPs prescribing antibiotics overall more often than is considered appropriate. POC testing may enhance the quality of antibiotic prescribing decisions if it can safely reverse decisions confidently made on clinical grounds alone to prescribe antibiotics.