RT Journal Article SR Electronic T1 Point-of-care testing, antibiotic prescribing, and prescribing confidence for respiratory tract infections in primary care: a prospective audit in 18 European countries JF BJGP Open JO BJGP Open FD Royal College of General Practitioners SP BJGPO.2021.0212 DO 10.3399/BJGPO.2021.0212 VO 6 IS 2 A1 Alike W van der Velden A1 Alma C van de Pol A1 Emily Bongard A1 Daniela Cianci A1 Rune Aabenhus A1 Anca Balan A1 Femke Böhmer A1 Valerija Bralić Lang A1 Pascale Bruno A1 Slawomir Chlabicz A1 Samuel Coenen A1 Annelies Colliers A1 Ana García-Sangenís A1 Hrachuhi Ghazaryan A1 Maciej Godycki-Ćwirko A1 Siri Jensen A1 Christos Lionis A1 Sanne R van der Linde A1 Lile Malania A1 Jozsef Pauer A1 Angela Tomacinschii A1 Akke Vellinga A1 Ihor Zastavnyy A1 Susanne Emmerich A1 Adam Zerda A1 Theo J Verheij A1 Herman Goossens A1 Christopher C Butler YR 2022 UL http://bjgpopen.org/content/6/2/BJGPO.2021.0212.abstract AB Background Between-country differences have been described in antibiotic prescribing for respiratory tract infection (RTI) in primary care, but not yet for diagnostic testing procedures and prescribing confidence.Aim To describe between-country differences in RTI management, particularly diagnostic testing and antibiotic prescribing, and investigate which factors relate to antibiotic prescribing and GPs’ prescribing confidence.Design & setting Prospective audit in 18 European countries.Method An audit of GP-registered patient, clinical, and management characteristics for patients presenting with sore throat and/or lower RTI (n = 4982), and GPs' confidence in their antibiotic prescribing decision. Factors related to antibiotic prescribing and confidence were analysed using multi-level logistic regression.Results Antibiotic prescribing proportions varied considerably: <20% in four countries, and >40% in six countries. There was also considerable variation in point-of-care (POC) testing (0% in Croatia, Moldova, and Romania, and >65% in Denmark and Norway, mainly for C-reactive protein [CRP] and group A streptococcal [strep A] infection), and in laboratory or hospital-based testing (<3% in Hungary, the Netherlands, and Spain, and >30% in Croatia, Georgia, Greece, and Moldova, mainly chest X-ray and white blood cell counting). Antibiotic prescribing was related to illness severity, comorbidity, age, fever, and country, but not to having performed a POC test. In nearly 90% of consultations, GPs were confident in their antibiotic prescribing decision.Conclusion Despite high confidence in decisions about antibiotic prescribing, there is considerable variation in the primary care of RTI in European countries, with GPs prescribing antibiotics overall more often than is considered appropriate. POC testing may enhance the quality of antibiotic prescribing decisions if it can safely reverse decisions confidently made on clinical grounds alone to prescribe antibiotics.