PT - JOURNAL ARTICLE AU - Humphrys, Elka AU - Walter, Fiona M AU - Rubin, Greg AU - Emery, Jon D AU - Johnson, Margaret AU - Richards, Anthony AU - Fitzgerald, Rebecca C AU - Viswanath, Yirupaiahgari KS AU - Burt, Jenni TI - Patient symptom experience prior to a diagnosis of oesophageal or gastric cancer: a multi-methods study AID - 10.3399/bjgpopen20X101001 DP - 2020 Apr 01 TA - BJGP Open PG - bjgpopen20X101001 VI - 4 IP - 1 4099 - http://bjgpopen.org/content/4/1/bjgpopen20X101001.short 4100 - http://bjgpopen.org/content/4/1/bjgpopen20X101001.full SO - BJGP Open2020 Apr 01; 4 AB - Background Late stage diagnosis of oesophageal and gastric cancer is common, which limits treatment options and contributes to poor survival.Aim To explore patients' understanding, experience and presentation of symptoms before a diagnosis of oesophageal or gastric cancer.Design & setting Between May 2016 and October 2017, all patients newly diagnosed with oesophageal or gastric cancer were identified at weekly multidisciplinary team meetings at two large hospitals in England. A total of 321 patients were invited to participate in a survey and secondary care medical record review; 127 (40%) participants responded (102 patients had oesophageal cancer and 25 had gastric cancer). Of these, 26 participated in an additional face-to-face interview.Method Survey and medical record data were analysed descriptively. Interviews were analysed using thematic analysis, informed by the Model of Pathways to Treatment.Results Participants experienced multiple symptoms before diagnosis. The most common symptom associated with oesophageal cancer was dysphagia (n = 66, 65%); for gastric cancer, fatigue or tiredness (n = 20, 80%) was the most common symptom. Understanding of heartburn, reflux and indigestion, and associated symptoms differed between participants and often contrasted with clinical perspectives. Bodily changes attributed to personal and/or lifestyle factors were self-managed, with presentation to primary care prompted when symptoms persisted, worsened, or impacted daily life, or were notably severe or unusual. Participants rarely presented all symptoms at the initial consultation.Conclusion The patient interval may be lengthened by misinterpretation of key terms, such as heartburn, or misattribution or non-recognition of important bodily changes. Clearly defined symptom awareness messages may encourage earlier help-seeking, while eliciting symptom experience and meanings in primary care consultations could prompt earlier referral and diagnosis.