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Research

Antibiotic prescriptions associated with a diagnosis of acute nasopharyngitis by general GPs in France: a retrospective study

Tran Tue Duong, Matta Matta, Beranger Lekens and Sylvain Diamantis
BJGP Open 2024; 8 (4): BJGPO.2024.0006. DOI: https://doi.org/10.3399/BJGPO.2024.0006
Tran Tue Duong
1 Service de Maladies Infectieuses et Tropicales, Centre Hospitalier de Melun, Melun, France
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Matta Matta
1 Service de Maladies Infectieuses et Tropicales, Centre Hospitalier de Melun, Melun, France
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  • For correspondence: matta-antoun.matta@ghsif.fr
Beranger Lekens
2 Cegedim SA, Boulogne-Billancourt, France
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Sylvain Diamantis
1 Service de Maladies Infectieuses et Tropicales, Centre Hospitalier de Melun, Melun, France
3 Dynamic Research Unit, Université Paris Est Créteil, Créteil, France
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    Figure 1. Antibiotic prescriptions for patients with nasopharyngitis (total number and percentage).
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    Figure 2. Antibiotic prescriptions 2018–2021.

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    Table 1. Types of drugs prescribed for patients with nasopharyngitis between January 2018 and December 2021, and their percentage of total drugs prescribed for these patients
    DrugNumber of prescribed medications% of the total prescribed medication volume for these patients95% confidence interval
    Paracetamol/acetaminophen498 62419.2419.19 to 19.29
    Nasal steroids475 42418.3418.29 to 18.39
    Cough medications454 89617.5517.50 to 17.60
    Nasal vasoconstrictors116 7374.504.47 to 4.53
    Antihistamines114 0294.394.37 to 4.41
    Non-steroidal anti-inflammatory drugs113 1464.364.33 to 4.39
    Penicillins112 0114.324.30 to 4.34
    Systemic steroids68 3142.632.61 to 2.65
    Macrolides40 7621.571.55 to 1.59
    Cephalosporins18 7690.720.71 to 0.73
    Other medications578 87222.3322.28 to 22.38
    Total2 591 584100–
    • View popup
    Table 2. Percentage of prescriptions for amoxicillin and mean of medications prescribed by patient’s age
    Patient’s age, yearsNumber of consultationsNumber of prescriptions for amoxicillin (%) (95% CI)Number of prescriptions for any medication (mean) (95% CI)
    0–9291 23953 005 (18.2) (18.13 to 18.27)718 803 (2.4) (2.457 to 2.463)**
    10–19132 05616 771 (12.7) (12.64 to 12.76)*346 116 (2.6) (2.616 to 2.624)**
    20 to 29105 4073159 (2.9) (2.87 to 2.93)*284 915 (2.7) (2.695 to 2.705)
    30–39112 7574141 (3.6) (3.65 to 3.64)*293 288 (2.6) (2.595 to 2.605)**
    40–49104 2125072 (4.8) (4.76 to 4.84)*259 824 (2.4) (2.486 to 2.494)**
    50–59109 5615599 (5.1) (5.06 to 5.14)*255 588 (2.3) (2.326 to 2.334)**
    60–69100 3585969 (5.95) (5.90 to 6.00)*218 808 (2.1) (2.176 to 2.184)**
    70–7972,5134335 (5.98) (5.93 to 6.03)*142 569 (1.9) (1.957 to 1.963)**
    80–8934093522 (10.3) (10.24 to 10.36)*62 794 (1.8) (1.836 to 1.844)**
    Total1 067 403102 089 (9.5)2 591 584 (2.4)
    • *P<0.001 (compared to 0–9 year-old group). **P<0.001 (compared to 20–29 year-old group). CI= confidence interval.

    • View popup
    Table 3. Percentage of antibiotics and mean of medications prescribed by doctor’s age
    Doctor’s age, yearsNumber of consultationsNumber of prescriptions for antibiotics (%) (95% CI)Number of prescriptions for any medication (mean) (95% CI)
    20–29253980 (3.2) (3.17 to 3.23)6368 (2.5) (2.457 to 2.543)
    30–39111 3679072 (8.1) (8.05 to 8.15)*256 744 (2.3) (2.296 to 2.304)**
    40–49198 01121 392 (10.8) (10.74 to 10.86)*478 269 (2.4) (2.407 to 2.413)**
    50–59340 29056 353 (16.6) (16.53 to 16.67)*835 258 (2.4) (2.453 to 2.457)**
    60–69383 39276 247 (19.9) (19.82 to 19.98)*941 403 (2.4) (2.453 to 2.458)**
    ≥7031 8048396 (26.4) (26.32 to 26.48)*71 913 (2.2) (2.252 to 2.268)**
    Total1 067 403171 540 (16.0)2 591 584 (2.4)
    • *P<0.001 (compared to 20–29 year-old group).**P<0.001 (compared to 20–29 year-old group). CI = confidence interval.

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Antibiotic prescriptions associated with a diagnosis of acute nasopharyngitis by general GPs in France: a retrospective study
Tran Tue Duong, Matta Matta, Beranger Lekens, Sylvain Diamantis
BJGP Open 2024; 8 (4): BJGPO.2024.0006. DOI: 10.3399/BJGPO.2024.0006

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Antibiotic prescriptions associated with a diagnosis of acute nasopharyngitis by general GPs in France: a retrospective study
Tran Tue Duong, Matta Matta, Beranger Lekens, Sylvain Diamantis
BJGP Open 2024; 8 (4): BJGPO.2024.0006. DOI: 10.3399/BJGPO.2024.0006
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Keywords

  • general practice
  • drug prescriptions
  • nasopharyngitis
  • amoxicillin
  • antibiotics

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