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Research

Designing a primary care pharmacist-led review for people treated with opioids for persistent pain: a multi-method qualitative study

Charlotte Woodcock, Nicola Cornwall, Lisa Dikomitis, Sarah A Harrisson, Simon White, Toby Helliwell, Roger Knaggs, Eleanor Hodgson, Tamar Pincus, Miriam Santer, Christian D Mallen, Julie Ashworth and Clare Jinks on behalf of the PROMPPT research team
BJGP Open 2024; 8 (3): BJGPO.2023.0221. DOI: https://doi.org/10.3399/BJGPO.2023.0221
Charlotte Woodcock
1 Centre for Musculoskeletal Health Research, School of Medicine, Keele University, Keele, UK
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  • ORCID record for Charlotte Woodcock
  • For correspondence: c.woodcock@keele.ac.uk
Nicola Cornwall
1 Centre for Musculoskeletal Health Research, School of Medicine, Keele University, Keele, UK
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Lisa Dikomitis
2 Centre for Health Services Studies and Kent and Medway Medical School, University of Kent, Canterbury, UK
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  • ORCID record for Lisa Dikomitis
Sarah A Harrisson
1 Centre for Musculoskeletal Health Research, School of Medicine, Keele University, Keele, UK
3 Midlands Partnership University NHS Foundation Trust, Haywood Hospital, High Lane, Burslem, Stoke on Trent, UK
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Simon White
4 School of Pharmacy and Bioengineering, Keele University, Keele, United Kingdom
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Toby Helliwell
1 Centre for Musculoskeletal Health Research, School of Medicine, Keele University, Keele, UK
3 Midlands Partnership University NHS Foundation Trust, Haywood Hospital, High Lane, Burslem, Stoke on Trent, UK
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Roger Knaggs
5 Division of Pharmacy Practice and Policy, School of Pharmacy, University of Nottingham, Nottingham, UK
6 Primary Integrated Community Services Ltd, Nottingham, UK
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Eleanor Hodgson
7 Leek Health Centre, Fountain Street, Leek, UK
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  • ORCID record for Eleanor Hodgson
Tamar Pincus
8 Department of Psychology, University of Southampton, Southampton, UK
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Miriam Santer
9 Primary Care Research Centre, University of Southampton, Southampton, UK
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Christian D Mallen
1 Centre for Musculoskeletal Health Research, School of Medicine, Keele University, Keele, UK
3 Midlands Partnership University NHS Foundation Trust, Haywood Hospital, High Lane, Burslem, Stoke on Trent, UK
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Julie Ashworth
1 Centre for Musculoskeletal Health Research, School of Medicine, Keele University, Keele, UK
3 Midlands Partnership University NHS Foundation Trust, Haywood Hospital, High Lane, Burslem, Stoke on Trent, UK
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Clare Jinks
1 Centre for Musculoskeletal Health Research, School of Medicine, Keele University, Keele, UK
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Article Figures & Data

Tables

    • View popup
    Table 1. Categorisation of patients by opioid strength based on a hierarchy of analgesic potency arising from a consensus study of UK GPs23
    WeakIntermediateStrong
    Co-codamol 8 mg/500 mgCodeine 30 mgMorphine
    Co-codamol 15 mg/500 mgCo-codamol 30 mg/500 mgOxycodone
    Codeine 15 mgDihydrocodeine 30 mgFentanyl
    Codeine 20 mgBuprenorphine patch ≥15 mcg/hourTapentadol
    Co-dydramol 10 mg/500 mgBuprenorphine sublingual 400 mcgDiamorphine
    Co-dydramol 20 mg/500 mgTramadol >37.5 mgHydromorphone
    Dihydrocodeine 20 mgPethidineDipipanone
    Co-proxamol 32.5 mg/325 mgPentazocineDextromoramide
    Tramadol 37.5 mg/500 mgMeptazinol
    Buprenorphine patch 5 or 10 mcg/hour
    Buprenorphine sublingual 200 mcg
    • View popup
    Table 2. Participant demographics of people living with persistent non-cancer pain (n = 15 interviews)
    Opioid strength Total
    Sex Age range (mean) years Weak Intermediate Strong
    Male55–83 (68.75)1124
    Female54–87 (70.73)24511
    All54–87 (70.20)35715
    • Opioid strength based on published categorisation for prescribed analgesics in primary care.23

    • View popup
    Table 3. TDF domains, facilitator and barrier sub-themes, and overarching themes for patients reducing opioids in the context of a PROMPPT review
    TDF domainSub-themeFaBbOverarching theme
    KnowledgeKnowing about and managing pain✓✓Learning to live with pain
    Behavioural regulationSelf-regulating pain management✓✓
    Environmental context and resourcesAccessible evidence-based resources✓
    Social influencesSocial support✓✓
    Social or professional role and identityChanging identities✓✓
    GoalsLive better with pain✓
    KnowledgeKnowing about reducing opioids✓✓Opioid reduction expectations
    Behavioural regulationMonitoring for quick effectiveness of opioid reduction✓✓
    Beliefs about capabilitiesUnable to cope with an opioid reduction✓
    Beliefs about consequencesConsequences of reducing opioids✓✓
    IntentionsIntention to reduce✓✓
    EmotionsAnxious about reducing opioids✓
    ReinforcementAvoid withdrawal✓
    Reduce if potential benefits perceived✓
    Social influencesPrescribed by healthcare professional✓Assuming a medical model
    ReinforcementOpioids are necessary✓
    Left on repeat prescription✓
    KnowledgePharmacist knowing about and managing pain within primary care✓Pharmacist-delivered reviews
    SkillsPatient-centred shared decision making✓
    Social influencesPatient–clinician relationship✓✓Pharmacist–patient relationship
    Supportive point of contact for pain management✓
    KnowledgePatient knowledge of PROMPPT review✓Patient engagement
    Environmental context and resourcesAccessibility of a PROMPPT review✓✓
    Beliefs about capabilitiesAble to discuss experiences of pain, medicines, and management✓
    Beliefs about consequencesWide-ranging benefits✓
    PROMPPT review concerns✓
    Provide a pharmacological solution✓
    IntentionsIntention to engage in a PROMPPT review✓✓
    GoalsFind a pharmacological solution✓
    Increase understanding of pain and medicines✓
    OptimismOptimistic a PROMPPT review will be helpful✓
    Uncertain of personal relevancy of a PROMPPT review✓
    • aF = facilitator. bB = barrier.

Supplementary Data

  • CW_10.3399BJGPO.2023.0221_supp.pdf -

    Supplementary material is not copyedited or typeset, and is published as supplied by the author(s). The author(s) retain(s) responsibility for its accuracy. 

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Designing a primary care pharmacist-led review for people treated with opioids for persistent pain: a multi-method qualitative study
Charlotte Woodcock, Nicola Cornwall, Lisa Dikomitis, Sarah A Harrisson, Simon White, Toby Helliwell, Roger Knaggs, Eleanor Hodgson, Tamar Pincus, Miriam Santer, Christian D Mallen, Julie Ashworth, Clare Jinks
BJGP Open 2024; 8 (3): BJGPO.2023.0221. DOI: 10.3399/BJGPO.2023.0221

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Designing a primary care pharmacist-led review for people treated with opioids for persistent pain: a multi-method qualitative study
Charlotte Woodcock, Nicola Cornwall, Lisa Dikomitis, Sarah A Harrisson, Simon White, Toby Helliwell, Roger Knaggs, Eleanor Hodgson, Tamar Pincus, Miriam Santer, Christian D Mallen, Julie Ashworth, Clare Jinks
BJGP Open 2024; 8 (3): BJGPO.2023.0221. DOI: 10.3399/BJGPO.2023.0221
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Keywords

  • pharmacists
  • analgesics, opioid
  • chronic pain

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  • General practitioner characteristics and video use in out-of-hours primary care: a register-based study
  • The impact of COVID-19 lockdowns on primary care contact among vulnerable populations in England: a controlled interrupted time series study
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