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Research

Redundant laboratory testing on referral from general practice to the outpatient clinic: a post-hoc analysis

Bram EL Vrijsen, Maarten J ten Berg, Wouter W van Solinge and Jan Westerink
BJGP Open 2022; 6 (1): BJGPO.2021.0134. DOI: https://doi.org/10.3399/BJGPO.2021.0134
Bram EL Vrijsen
1 Department of Internal Medicine, Division Internal Medicine and Dermatology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
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  • ORCID record for Bram EL Vrijsen
  • For correspondence: b.e.l.vrijsen@umcutrecht.nl
Maarten J ten Berg
2 Central Diagnostic Laboratory, Division Laboratories, Pharmacy and Biomedical Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
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Wouter W van Solinge
2 Central Diagnostic Laboratory, Division Laboratories, Pharmacy and Biomedical Genetics, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
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Jan Westerink
1 Department of Internal Medicine, Division Internal Medicine and Dermatology, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands
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Article Figures & Data

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    Table 1. Baseline characteristics
    CharacteristicPre-visit testingPost-visit testing
    Total, n 104191
    Age, years (95% CI)53.4 (49.7 to 57.1)52.3 (49.6 to 54.9)
    Female, n (%)66 (63)129 (68)
    Referral reason, n (%)a
    Abdominal complaints12 (12)23 (12)
    Abnormal laboratory test16 (15)28 (15)
    Anaemia12 (12)28 (15)
    Fatigue37 (36)47 (25)
    Lymphadenopathy/suspected malignancy1 (1)8 (4)
    Weight loss15 (14)29 (15)
    Other24 (23)43 (23)
    • aCategories are not exclusive.

    • View popup
    Table 2. Number of repeats of primary care physician’s tests depending on laboratory testing strategy in the outpatient clinic
    Tests, normal results, and repeat tests,
    median (IQR)
    Pre-visittesting
    (n = 104)
    Post-visittesting
    (n = 191)
    P value
    Tests12.5 (8.8–17.0)14.0 (10.0–18.0)—
    Normal results9.5 (6.0–14.0)11.0 (8.0–14.0)—
    Repeats overall9.5 (6.0–13.0)8.0 (4.0–11.0) P<0.001a
    Repeats of normal results8.0 (3.8–10.0)5.0 (3.0–9.0) P<0.001a
    • aStatistically tested using the Wilcoxon rank-sum test. IQR = interquartile range.

    • View popup
    Table 3. Ten most commonly ordered tests with repetition rates and rates of normal tests remaining normal on retesting
    TestTests by primary care physician, nRepeats, n (%)Normal results on first test being repeated,
    n (%)
    Normal repeats remaining normal,
    n (%)
    Haemoglobin247217 (88)141 (84)134 (95)
    MCV237204 (86)170 (85)163 (96)
    Leucocytes227198 (87)154 (85)136 (88)
    Creatinine213185 (87)152 (85)147 (97)
    ESR198151 (76)96 (77)95 (99)
    TSH192141 (73)129 (75)125 (97)
    Glucose191114 (60)73 (57)57 (78)
    Thrombocytes188162 (86)142 (85)136 (96)
    ALT164136 (83)111 (80)103 (93)
    Leucocyte differential156114 (73)106 (72)82 (77)
    • ALT = alanine transaminase. ESR = erythrocyte sedimentation rate. MCV = mean corpuscular volume. TSH = thyroid stimulating hormone.

    • View popup
    Table 4. Tests with the highest rates of normal test results becoming abnormal on retesting
    TestNormal results being repeated,
    n (% of normal results)
    Normal repeats remaining normal,
    n (% of normal repeats)
    Urine screening14 (82)4 (29)
    Creatine kinase2 (22)1 (50)
    Iron3 (14)2 (67)
    Cholesterol4 (6)3 (75)
    Reticulocytes8 (29)6 (75)
    Leucocyte differential106 (72)82 (77)
    Potassium90 (74)70 (78)
    Glucose73 (57)57 (78)
    Sodium83 (75)67 (81)
    Ferritin11 (31)9 (82)

Supplementary Data

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Test: Supplementary material is not copyedited or typeset, and is published as supplied by the author(s). The author(s) retain(s) responsibility for its accuracy.

Files in this Data Supplement:

  • Adobe PDF - BJGPO.2021.0134.full.pdf

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Test: Supplementary material is not copyedited or typeset, and is published as supplied by the author(s). The author(s) retain(s) responsibility for its accuracy.

Files in this Data Supplement:

  • Adobe PDF - BJGPO.2021.0134.full.pdf
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Redundant laboratory testing on referral from general practice to the outpatient clinic: a post-hoc analysis
Bram EL Vrijsen, Maarten J ten Berg, Wouter W van Solinge, Jan Westerink
BJGP Open 2022; 6 (1): BJGPO.2021.0134. DOI: 10.3399/BJGPO.2021.0134

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Redundant laboratory testing on referral from general practice to the outpatient clinic: a post-hoc analysis
Bram EL Vrijsen, Maarten J ten Berg, Wouter W van Solinge, Jan Westerink
BJGP Open 2022; 6 (1): BJGPO.2021.0134. DOI: 10.3399/BJGPO.2021.0134
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Keywords

  • Clinical Laboratory Techniques
  • clinical laboratory services
  • General Practice
  • hospitals
  • laboratories
  • medical overuse
  • outpatient clinics, hospital
  • referral and consultation

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