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Research

PRINCIPLE trial demonstrates scope for in-pandemic improvement in primary care antibiotic stewardship: a retrospective sentinel network cohort study

Simon de Lusignan, Mark Joy, Julian Sherlock, Manasa Tripathy, Oliver van Hecke, Kome Gbinigie, John Williams, Christopher Butler and FD Richard Hobbs
BJGP Open 2021; 5 (5): BJGPO.2021.0087. DOI: https://doi.org/10.3399/BJGPO.2021.0087
Simon de Lusignan
1 Professor of Primary Care & Clinical Informatics, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
MSc, MD(Res), FRCGP
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  • ORCID record for Simon de Lusignan
  • For correspondence: simon.delusignan{at}phc.ox.ac.uk
Mark Joy
2 Senior Researcher, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
MSc, PhD
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  • ORCID record for Mark Joy
Julian Sherlock
3 SQL Developer, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
BA
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  • ORCID record for Julian Sherlock
Manasa Tripathy
4 Research Officer/Practice Liaison Officer, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
BSc (Hons), MSc
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  • ORCID record for Manasa Tripathy
Oliver van Hecke
5 NIHR Academic Clinical Lecturer, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
MBChB (Pret), DMJ (Clin), MRCGP, FRACGP, DPhil
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Kome Gbinigie
6 GP and DPhil Student, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
MA(Cantab), MB BChir, MRCGP, DRCOG, DfSRH, PGCert(Health Research)
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John Williams
7 Senior Research Fellow, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
MBBChir, FRCGP, MSc
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Christopher Butler
8 Professor of Primary Care, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
BA, MBChB, DCH, CCH MD, FRCGP (Hon), FFPH, FMedSci
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FD Richard Hobbs
9 Head of Department, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
CBE, FMedSci, FRCGP, FRCP (London), FESC, FRCP (Edin), MA (Ox)
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  • For correspondence: richard.hobbs{at}phc.ox.ac.uk
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Article Information

vol. 5 no. 5 BJGPO.2021.0087
DOI 
https://doi.org/10.3399/BJGPO.2021.0087
PubMed 
34312163

Published By 
Royal College of General Practitioners
History 
  • Received May 17, 2021
  • Accepted June 9, 2021
  • Published online October 26, 2021.

Article Versions

  • Previous version (July 26, 2021 - 06:50).
  • Previous version (September 28, 2021 - 16:30).
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Copyright & Usage 
Copyright © 2021, The Authors This article is Open Access: CC BY license (https://creativecommons.org/licenses/by/4.0/)

Author Information

  1. Simon de Lusignan, MSc, MD(Res), FRCGP1,*,
  2. Mark Joy, MSc, PhD2,
  3. Julian Sherlock, BA3,
  4. Manasa Tripathy, BSc (Hons), MSc4,
  5. Oliver van Hecke, MBChB (Pret), DMJ (Clin), MRCGP, FRACGP, DPhil5,
  6. Kome Gbinigie, MA(Cantab), MB BChir, MRCGP, DRCOG, DfSRH, PGCert(Health Research)6,
  7. John Williams, MBBChir, FRCGP, MSc7,
  8. Christopher Butler, BA, MBChB, DCH, CCH MD, FRCGP (Hon), FFPH, FMedSci8 and
  9. FD Richard Hobbs, CBE, FMedSci, FRCGP, FRCP (London), FESC, FRCP (Edin), MA (Ox)9,*
  1. 1 Professor of Primary Care & Clinical Informatics, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
  2. 2 Senior Researcher, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
  3. 3 SQL Developer, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
  4. 4 Research Officer/Practice Liaison Officer, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
  5. 5 NIHR Academic Clinical Lecturer, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
  6. 6 GP and DPhil Student, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
  7. 7 Senior Research Fellow, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
  8. 8 Professor of Primary Care, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
  9. 9 Head of Department, Nuffield Department of Primary Care Health Sciences, University of Oxford, Oxford, UK
  1. ↵ *For correspondence:
    Simon de Lusignan, simon.delusignan{at}phc.ox.ac.uk
  2. ↵ *For correspondence:
    FD Richard Hobbs, richard.hobbs{at}phc.ox.ac.uk
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PRINCIPLE trial demonstrates scope for in-pandemic improvement in primary care antibiotic stewardship: a retrospective sentinel network cohort study
Simon de Lusignan, Mark Joy, Julian Sherlock, Manasa Tripathy, Oliver van Hecke, Kome Gbinigie, John Williams, Christopher Butler, FD Richard Hobbs
BJGP Open 2021; 5 (5): BJGPO.2021.0087. DOI: 10.3399/BJGPO.2021.0087

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PRINCIPLE trial demonstrates scope for in-pandemic improvement in primary care antibiotic stewardship: a retrospective sentinel network cohort study
Simon de Lusignan, Mark Joy, Julian Sherlock, Manasa Tripathy, Oliver van Hecke, Kome Gbinigie, John Williams, Christopher Butler, FD Richard Hobbs
BJGP Open 2021; 5 (5): BJGPO.2021.0087. DOI: 10.3399/BJGPO.2021.0087
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Keywords

  • primary health care
  • COVID-19
  • clinical trial
  • pandemics
  • medical records systems, computerized
  • antimicrobial stewardship

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  • Responses to the inverse care law in Scottish general practice and the role of the Deep End project: a qualitative study
  • Deprivation and primary care network performance: a national cross-sectional study of the Investment and Impact Fund scheme
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