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Research

Is there an association between long-term antibiotics for acne and subsequent infection sequelae and antimicrobial resistance? A systematic review

Ketaki Bhate, Liang-Yu Lin, John S Barbieri, Clémence Leyrat, Susan Hopkins, Richard Stabler, Laura Shallcross, Liam Smeeth, Nick Francis, Rohini Mathur, Sinéad M Langan and Sarah-Jo Sinnott
BJGP Open 2021; 5 (3): BJGPO.2020.0181. DOI: https://doi.org/10.3399/BJGPO.2020.0181
Ketaki Bhate
1 Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
MBBS, MSc, MRCP (Dermatology)
Roles: Dr
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  • ORCID record for Ketaki Bhate
  • For correspondence: ketaki.bhate@lshtm.ac.uk
Liang-Yu Lin
1 Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
MD, MSc
Roles: Dr
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John S Barbieri
2 University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA
MD
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Clémence Leyrat
1 Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
MSc, PhD
Roles: Dr
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Susan Hopkins
3 AMR Division, Public Health England, London, UK
BA, MB BCh, BAO, MSc, FRCPI, FRCP
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Richard Stabler
4 Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
PhD
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Laura Shallcross
5 Faculty of Population Health Sciences, University College London, London, UK
BA, MBBS, MSc, PhD
Roles: Dr
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  • ORCID record for Laura Shallcross
Liam Smeeth
1 Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
MBChB, FRCGP, FFPH, FRCP, MSc, PhD, FMedSci
Roles: Professor
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Nick Francis
6 School of Primary Care, Population Sciences and Medical Education, University of Southampton, Southampton, UK
PhD, MD, BA, PGD (Epidemiology), MRCGP
Roles: Professor
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Rohini Mathur
1 Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
BSc, MSc, PhD
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Sinéad M Langan
1 Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
FRCP, MSc, PhD
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Sarah-Jo Sinnott
1 Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
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Article Information

vol. 5 no. 3 BJGPO.2020.0181
DOI 
https://doi.org/10.3399/BJGPO.2020.0181
PubMed 
33687983

Published By 
Royal College of General Practitioners
History 
  • Received December 7, 2020
  • Accepted January 19, 2021
  • Published online June 30, 2021.

Article Versions

  • Previous version (March 9, 2021 - 03:35).
  • Previous version (April 6, 2021 - 16:30).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2021, The Authors This article is Open Access: CC BY license (https://creativecommons.org/licenses/by/4.0/)

Author Information

  1. Ketaki Bhate, Dr, MBBS, MSc, MRCP (Dermatology)1,*,
  2. Liang-Yu Lin, Dr, MD, MSc1,
  3. John S Barbieri, Dr, MD2,
  4. Clémence Leyrat, Dr, MSc, PhD1,
  5. Susan Hopkins, Dr, BA, MB BCh, BAO, MSc, FRCPI, FRCP3,
  6. Richard Stabler, Dr, PhD4,
  7. Laura Shallcross, Dr, BA, MBBS, MSc, PhD5,
  8. Liam Smeeth, Professor, MBChB, FRCGP, FFPH, FRCP, MSc, PhD, FMedSci1,
  9. Nick Francis, Professor, PhD, MD, BA, PGD (Epidemiology), MRCGP6,
  10. Rohini Mathur, Dr, BSc, MSc, PhD1,
  11. Sinéad M Langan, Professor, FRCP, MSc, PhD1 and
  12. Sarah-Jo Sinnott, Dr, BPharm, MPharm, PhD, MPSI1
  1. 1 Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
  2. 2 University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA
  3. 3 AMR Division, Public Health England, London, UK
  4. 4 Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
  5. 5 Faculty of Population Health Sciences, University College London, London, UK
  6. 6 School of Primary Care, Population Sciences and Medical Education, University of Southampton, Southampton, UK
  1. ↵ *For correspondence:
    Ketaki Bhate, ketaki.bhate{at}lshtm.ac.uk
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Is there an association between long-term antibiotics for acne and subsequent infection sequelae and antimicrobial resistance? A systematic review
Ketaki Bhate, Liang-Yu Lin, John S Barbieri, Clémence Leyrat, Susan Hopkins, Richard Stabler, Laura Shallcross, Liam Smeeth, Nick Francis, Rohini Mathur, Sinéad M Langan, Sarah-Jo Sinnott
BJGP Open 2021; 5 (3): BJGPO.2020.0181. DOI: 10.3399/BJGPO.2020.0181

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Is there an association between long-term antibiotics for acne and subsequent infection sequelae and antimicrobial resistance? A systematic review
Ketaki Bhate, Liang-Yu Lin, John S Barbieri, Clémence Leyrat, Susan Hopkins, Richard Stabler, Laura Shallcross, Liam Smeeth, Nick Francis, Rohini Mathur, Sinéad M Langan, Sarah-Jo Sinnott
BJGP Open 2021; 5 (3): BJGPO.2020.0181. DOI: 10.3399/BJGPO.2020.0181
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Keywords

  • Acne vulgaris
  • antibiotic
  • antimicrobial resistance
  • tetracycline
  • macrolides
  • dihydrofolate reductase inhibitor

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