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Protocol

Evaluation of a primary care-based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar, or other psychoses: study protocol for a cluster randomised controlled trial

Humera Plappert, Charley Hobson-Merrett, Bliss Gibbons, Elina Baker, Sheridan Bevan, Michael Clark, Siobhan Creanor, Linda Davies, Rebecca Denyer, Julia Frost, Linda Gask, John Gibson, Laura Gill, Ruth Gwernan-Jones, Pollyanna Hardy, Joanne Hosking, Peter Huxley, Alison Jeffrey, Benjamin Jones, Steven Marwaha, Vanessa Pinold, Claire Planner, Tim Rawcliffe, Siobhan Reilly, Debra Richards, Lynsey Williams, Max Birchwood and Richard Byng
BJGP Open 2021; 5 (3): BJGPO.2021.0033. DOI: https://doi.org/10.3399/BJGPO.2021.0033
Humera Plappert
1 School of Psychology, University of Birmingham, Birmingham, UK
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  • For correspondence: h.plappert@bham.ac.uk
Charley Hobson-Merrett
2 Community and Primary Care Research Group- Faculty of Medicine, University of Plymouth, Plymouth, UK
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Bliss Gibbons
3 Coventry and Warwickshire Partnership NHS Trust, Coventry, UK
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Elina Baker
4 Institute of Health Research, University of Exeter, Exeter, UK
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Sheridan Bevan
5 Birmingham Clinical Trials Unit, Birmingham University, Birmingham, UK
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Michael Clark
6 London School of Economics and Political Science, London, UK
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Siobhan Creanor
7 Exeter Clinical Trials Unit, University of Exeter, Exeter, UK
8 Peninsula Clinical Trials Unit, University of Plymouth, Plymouth, UK
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Linda Davies
9 Division of Population Health - Health Services Research & Primary Care, University of Manchester, Manchester, UK
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Rebecca Denyer
1 School of Psychology, University of Birmingham, Birmingham, UK
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Julia Frost
4 Institute of Health Research, University of Exeter, Exeter, UK
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Linda Gask
10 Psychiatry, University of Manchester, Manchester, UK
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John Gibson
11 McPin Foundation, London, UK
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Laura Gill
2 Community and Primary Care Research Group- Faculty of Medicine, University of Plymouth, Plymouth, UK
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Ruth Gwernan-Jones
4 Institute of Health Research, University of Exeter, Exeter, UK
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Pollyanna Hardy
5 Birmingham Clinical Trials Unit, Birmingham University, Birmingham, UK
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Joanne Hosking
2 Community and Primary Care Research Group- Faculty of Medicine, University of Plymouth, Plymouth, UK
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Peter Huxley
12 School of Health Sciences, Bangor University, UK
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Alison Jeffrey
8 Peninsula Clinical Trials Unit, University of Plymouth, Plymouth, UK
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Benjamin Jones
7 Exeter Clinical Trials Unit, University of Exeter, Exeter, UK
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Steven Marwaha
1 School of Psychology, University of Birmingham, Birmingham, UK
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Vanessa Pinold
11 McPin Foundation, London, UK
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Claire Planner
9 Division of Population Health - Health Services Research & Primary Care, University of Manchester, Manchester, UK
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Tim Rawcliffe
13 Lancashire Care NHS Foundation Trust, Preston, UK
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Siobhan Reilly
14 Faculty of Health Studies, University of Bradford, Bradford, UK
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Debra Richards
2 Community and Primary Care Research Group- Faculty of Medicine, University of Plymouth, Plymouth, UK
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Lynsey Williams
2 Community and Primary Care Research Group- Faculty of Medicine, University of Plymouth, Plymouth, UK
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Max Birchwood
15 Warwick Medical School, University of Warwick, Warwick, UK
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Richard Byng
2 Community and Primary Care Research Group- Faculty of Medicine, University of Plymouth, Plymouth, UK
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Abstract

Background Current NHS policy encourages an integrated approach to provision of mental and physical care for individuals with long term mental health problems. The ‘PARTNERS2’ complex intervention is designed to support individuals with psychosis in a primary care setting.

Aim The trial will evaluate the clinical and cost-effectiveness of the PARTNERS2 intervention.

Design & setting This is a cluster randomised controlled superiority trial comparing collaborative care (PARTNERS2) with usual care, with an internal pilot to assess feasibility. The setting will be primary care within four trial recruitment areas: Birmingham & Solihull, Cornwall, Plymouth, and Somerset. GP practices are randomised 1:1 to either (a) the PARTNERS2 intervention plus modified standard care (‘intervention’); or (b) standard care only (‘control’).

Method PARTNERS2 is a flexible, general practice-based, person-centred, coaching-based intervention aimed at addressing mental health, physical health, and social care needs. Two hundred eligible individuals from 39 GP practices are taking part. They were recruited through identification from secondary and primary care databases. The primary hypothesis is quality of life (QOL). Secondary outcomes include: mental wellbeing, time use, recovery, and process of physical care. A process evaluation will assess fidelity of intervention delivery, test hypothesised mechanisms of action, and look for unintended consequences. An economic evaluation will estimate its cost-effectiveness. Intervention delivery and follow-up have been modified during the COVID-19 pandemic.

Conclusion The overarching aim is to establish the clinical and cost-effectiveness of the model for adults with a diagnosis of schizophrenia, bipolar, or other types of psychoses.

  • Randomized Controlled Trial
  • Protocol
  • Collaborative Care
  • Schizophrenia
  • Bipolar Disorder
  • Psychotic Disorders
  • Received March 1, 2021.
  • Accepted March 9, 2021.
  • Copyright © 2021, The Authors

This article is Open Access: CC BY license (https://creativecommons.org/licenses/by/4.0/)

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Evaluation of a primary care-based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar, or other psychoses: study protocol for a cluster randomised controlled trial
Humera Plappert, Charley Hobson-Merrett, Bliss Gibbons, Elina Baker, Sheridan Bevan, Michael Clark, Siobhan Creanor, Linda Davies, Rebecca Denyer, Julia Frost, Linda Gask, John Gibson, Laura Gill, Ruth Gwernan-Jones, Pollyanna Hardy, Joanne Hosking, Peter Huxley, Alison Jeffrey, Benjamin Jones, Steven Marwaha, Vanessa Pinold, Claire Planner, Tim Rawcliffe, Siobhan Reilly, Debra Richards, Lynsey Williams, Max Birchwood, Richard Byng
BJGP Open 2021; 5 (3): BJGPO.2021.0033. DOI: 10.3399/BJGPO.2021.0033

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Evaluation of a primary care-based collaborative care model (PARTNERS2) for people with diagnoses of schizophrenia, bipolar, or other psychoses: study protocol for a cluster randomised controlled trial
Humera Plappert, Charley Hobson-Merrett, Bliss Gibbons, Elina Baker, Sheridan Bevan, Michael Clark, Siobhan Creanor, Linda Davies, Rebecca Denyer, Julia Frost, Linda Gask, John Gibson, Laura Gill, Ruth Gwernan-Jones, Pollyanna Hardy, Joanne Hosking, Peter Huxley, Alison Jeffrey, Benjamin Jones, Steven Marwaha, Vanessa Pinold, Claire Planner, Tim Rawcliffe, Siobhan Reilly, Debra Richards, Lynsey Williams, Max Birchwood, Richard Byng
BJGP Open 2021; 5 (3): BJGPO.2021.0033. DOI: 10.3399/BJGPO.2021.0033
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Keywords

  • Randomized Controlled Trial
  • Protocol
  • Collaborative Care
  • Schizophrenia
  • Bipolar Disorder
  • Psychotic Disorders

More in this TOC Section

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