Article Figures & Data
Figures
- Figure 1. Number of women prescribed valproate between 2017 and 2020 in East London
- Figure 2. Change in pre-conception or contraception advice (purple), prescribed contraception (blue), and women receiving advice and/or contraception (orange), normalised to the number of women prescribed valproate
Tables
- Table 1. Demographic characteristics of 330 women aged 15–44 years prescribed sodium valproate between 1 October 2017 and 1 January 2020 in East London
Age, yearsa n (%) 15–19 38 (12) 20–24 22 (7) 25–29 54 (16) 30–34 69 (21) 35–39 60 (18) ≥40 87 (26) Ethnic group a White 150 (45) Black 49 (15) South Asian 87 (26) Other 22 (7) Unknown 22 (7) Received pre-conception or contraception advice b 151 (46) Prescribed contraception b 90 (27) Prescribed LARCc 48 (53) Prescribed non-LARCc 42 (47) Received advice or contraception b 191 (58) aData relate to most recent record for age and ethnic group. bAt least once during study period. cLong-acting reversible contraception (LARC): copper intrauterine device, levonorgestrel 13.5 mg/19.5 mg/52 mg intrauterine system, and progestogen-only implant. Non-LARC contraception: combined hormonal contraception including combined contraceptive pill, transdermal patch and vaginal ring, progestogen-only pill, progestogen-only injectable depot medroxyprogesterone acetate, condoms, and diaphragms.
- Table 2. Pregnancy and pregnancy rates by quarter between 1 October 2017 and 1 January 2020 in East London
Quarter 10/17 01/18 04/18 07/18 10/18 01/19 04/19 07/19 10/19 01/20 Total, n 214 198 194 179 178 162 148 143 142 136 Pregnancies, n a 4 1 1 0 0 1 0 1 0 1 Pregnancy rate (average per 1000 population) 9.9 2.8 aNew pregnancies in this quarter; corrected for one termination or miscarriage.
- Table 3. Indication for valproate for women included in the first and last quarters of the study period
Valproateindicationa Dataextraction from 1 Oct 2017 Data extraction from 1 Jan 2020 n (%) n (%) Epilepsy 139 (65) 88 (65) Bipolar disorder 31 (14) 20 (15) Migraine 4 (2) 2 (1) Learning difficulties 5 (2) 5 (4) Other or unknown 35 (16) 21 (15) Total patients 214 (100) 136 (100) aLikely indication inferred from recorded long-term conditions on electronic health record.
Supplementary Data
- BJGPO.2020.0104.pdf -
Supplementary material is not copyedited or typeset, and is published as supplied by the author(s). The author(s) retain(s) responsibility for its accuracy.
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