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Research

Patients’ and health professionals’ attitudes and perceptions towards the initiation of preventive drugs for primary prevention of cardiovascular disease: a systematic review of qualitative studies

Olla Qadi, Nakawala Lufumpa, Nicola Adderley, Danai Bem, Tom Marshall and Farina Kokab
BJGP Open 2020; 4 (5): bjgpopen20X101087. DOI: https://doi.org/10.3399/bjgpopen20X101087
Olla Qadi
1PhD student, Institute of Applied Health Research, University of Birmingham, Birmingham, UK
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Nakawala Lufumpa
1PhD student, Institute of Applied Health Research, University of Birmingham, Birmingham, UK
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Nicola Adderley
2Lecturer in Health Informatics and Epidemiology, Institute of Applied Health Research, University of Birmingham, Birmingham, UK
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  • ORCID record for Nicola Adderley
  • For correspondence: n.j.adderley{at}bham.ac.uk
Danai Bem
3Honorary Research Fellow, Institute of Applied Health Research, University of Birmingham, Birmingham, UK
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Tom Marshall
4Professor of Public Health & Primary Care, Institute of Applied Health Research, University of Birmingham, Birmingham, UK
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Farina Kokab
5Research Fellow, Institute of Applied Health Research, University of Birmingham, Birmingham, UK
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Article Figures & Data

Figures

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    Figure 1. PRISMA flow diagram
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    Figure 2. Diagram of patient and health professional related themes

Tables

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    Table 1. Summary of Sample, Phenomenon of Interest, Design, Evaluation, Research (SPIDER) framework
    Sample
    • Health professionals (GPs or nurse practitioners) who prescribe statins or antihypertensive drugs.

    • Patients eligible for cardiovascular preventive drugs or offered a prescription of statin or an antihypertensive drug for primary prevention of cardiovascular disease.

    Phenomenon of InterestThe initiation or prescription of statins or antihypertensive drugs.
    DesignStudies including qualitative data collection or analysis methods.
    EvaluationAttitudes, perceptions, views, or experiences of health professionals or patients related to the initiation of cardiovascular preventive drugs for primary prevention.
    Research typeQualitative and mixed methods studies.
    • View popup
    Table 2. Characteristics of included studies
    AuthorsStudy titleCardiovascular drugHealth professionals,nPatients,nStudy designData collectionData analysisQuality of study
    UK
    Gale, 201118Attitudes of patients and GPs towards medication for primary prevention of CVD after they had received detailed information about CVD risk and the absolute benefits of preventive medicine.Cardiovascular preventive drugs (statin and antihypertensive drugs)1317QualitativePatients: face to face interviewsGPs: interviewsThematic analysisGood
    Turner, 201334Reasons for the variation in statin uptake by high risk patientsStatin428QualitativePatients: 10 minutes telephone interviews.GPs: 30 minutes face to face interviews.Thematic analysisFair
    Virdee, 201332Primary care physicians’ and practice nurses’ attitude towards using the polypill for CVD preventionPolypill16 (11 physicians, five practice nurses)–QualitativeSemi-structured interviews and transcribed verbatim.Thematic analysis.Good
    Virdee, 201533Patient attitudes about the use of a polypill for CVD preventionPolypill–17QualitativeSemi-structured interviews.Thematic analysis.Good
    Sweden
    Hultberg, 201231GPs’ descriptions of their thoughts and actions when prescribing cardiovascular preventive drugsCardiovascular preventive drugs (no mention of specific drugs)14–QualitativeGroup interviews of GPs practising together.Qualitative content analysis.Good
    • CVD
      cardiovascular disease
    • View popup
    Table 3. COREQ checklist detailing studies’ reporting of each item
    ItemStudies reporting itemaStudies reporting item, n (%)
    Domain 1: Research team and reflexivity
    Personal characteristics
    Interviewer/facilitator(18, 31–33)4 (80)
    Credentials(33)1 (20)
    Occupation(33)1 (20)
    Sex–0
    Experience and training(33)1 (20)
    Relationship with participants
    Relationship established–0
    Participant knowledge of the interviewer–0
    Interviewer characteristics–0
    Domain 2: study design
    Theoretical framework
    Methodological orientation and theory(31–34)4 (80)
    Participant selection
    Sampling(18, 31–34)5 (100)
    Method of approach(18, 31–34)5 (100)
    Sample size(18, 31–34)5 (100)
    Non-participation(32–34)3 (60)
    Setting
    Setting of data collection(18, 31–34)5 (100)
    Presence of non-participants–0
    Description of sample(18, 31–34)5 (100)
    Data collection
    Interview guide(18, 31–34)5 (100)
    Repeat interviews(18, 31)2 (40)
    Audio/visual recording(18, 31–34)5(100)
    Field notes(31–34)4 (80)
    Duration(32–34)3 (60)
    Data saturation(18, 31–33)4 (80)
    Transcripts returned(32, 33)2 (40)
    Domain 3: analysis and findings
    Data analysis
    Number of data coders(18, 31–33)4 (80)
    Description of the coding tree(31–33)3 (60)
    Derivation of themes(18, 31–34)5 (100)
    Software(32, 33)2 (40)
    Participant checking–0
    Reporting
    Quotations presented(18, 31–34)5 (100)
    Data and findings consistent(18, 31–34)5 (100)
    Clarity of major themes(18, 31–34)5 (100)
    Clarity of minor themes(18, 31–34)5 (100)
    • aStudies are identified by their reference number.18,31–34

    • COREQ
      Consolidated Criteria for Reporting Qualitative Research

Supplementary Data

  • bjgpopen20X101087_Supp.pdf -

    Supplementary material is not copyedited or typeset, and is published as supplied by the author(s). The author(s) retain(s) responsibility for its accuracy.

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Patients’ and health professionals’ attitudes and perceptions towards the initiation of preventive drugs for primary prevention of cardiovascular disease: a systematic review of qualitative studies
Olla Qadi, Nakawala Lufumpa, Nicola Adderley, Danai Bem, Tom Marshall, Farina Kokab
BJGP Open 2020; 4 (5): bjgpopen20X101087. DOI: 10.3399/bjgpopen20X101087

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Patients’ and health professionals’ attitudes and perceptions towards the initiation of preventive drugs for primary prevention of cardiovascular disease: a systematic review of qualitative studies
Olla Qadi, Nakawala Lufumpa, Nicola Adderley, Danai Bem, Tom Marshall, Farina Kokab
BJGP Open 2020; 4 (5): bjgpopen20X101087. DOI: 10.3399/bjgpopen20X101087
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Keywords

  • qualitative research
  • Cardiovascular disease
  • statins
  • antihypertensive drugs
  • primary prevention

More in this TOC Section

  • UK primary care teams and social determinants of health intervention: a qualitative study
  • Responses to the inverse care law in Scottish general practice and the role of the Deep End project: a qualitative study
  • Deprivation and primary care network performance: a national cross-sectional study of the Investment and Impact Fund scheme
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